Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

Modern electroencephalographic (EEG) technology contributed to the appreciation that the
EEG signal outside the classical Berger frequency band contains important information. In …

To understand dynamic cognitive processes, the high time resolution of EEG/MEG is
invaluable. EEG/MEG signals can play an important role in providing measures of functional …

The kainic acid model of temporal lobe epilepsy has greatly contributed to the
understanding of the molecular, cellular and pharmacological mechanisms underlying …

Temporal lobe epilepsy is the most common type of epilepsy in adults, is often medically
refractory, and due to broad actions and long-time scales, current systemic treatments have …

Experimental models of epilepsy are useful to identify potential mechanisms of
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …

Temporal lobe epilepsy (TLE) is characterized by debilitating, recurring seizures and an
increased risk for cognitive deficits. Mossy cells (MCs) are key neurons in the hippocampal …

The discovery that electroencephalography (EEG) contains useful information at frequencies
above the traditional 80Hz limit has had a profound impact on our understanding of brain …

High-frequency oscillations (100–200 Hz), termed ripples, have been identified in
hippocampal (Hip) and entorhinal cortical (EC) areas of rodents and humans. In contrast …

Mesial temporal lobe epilepsy is the most common form of human epilepsy, and its
pathophysiological substrate is usually hippocampal sclerosis, the most common …