Mechanisms of Antibiotic Failure During Staphylococcus aureus Osteomyelitis
BD Gimza, JE Cassat - Frontiers in immunology, 2021 - frontiersin.org
Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing
both superficial and invasive, life-threatening diseases. Of the invasive disease …
both superficial and invasive, life-threatening diseases. Of the invasive disease …
β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium
JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
Bactericidal synergism between phage endolysin Ply2660 and cathelicidin LL-37 against vancomycin-resistant Enterococcus faecalis biofilms
H Zhang, X Zhang, S Liang, J Wang, Y Zhu… - npj Biofilms and …, 2023 - nature.com
Antibiotic resistance and the ability to form biofilms of Enterococcus faecalis have
compromised the choice of therapeutic options, which triggered the search for new …
compromised the choice of therapeutic options, which triggered the search for new …
Host-acting antibacterial compounds combat cytosolic bacteria
X Liu, Y Wu, C Mao, J Shen, K Zhu - Trends in Microbiology, 2022 - cell.com
The sharp increase in infections associated with multidrug-resistant (MDR) bacterial
pathogens that have seriously compromised traditional chemotherapeutics is becoming a …
pathogens that have seriously compromised traditional chemotherapeutics is becoming a …
Lysostaphin: engineering and potentiation toward better applications
Lysostaphin is a potent bacteriolytic enzyme with endopeptidase activity against the
common pathogen Staphylococcus aureus. By digesting the pentaglycine crossbridge in the …
common pathogen Staphylococcus aureus. By digesting the pentaglycine crossbridge in the …
Non-antibiotic strategies for prevention and treatment of internalized Staphylococcus aureus
J Li, Q Wen, F Gu, L An, T Yu - Frontiers in microbiology, 2022 - frontiersin.org
Staphylococcus aureus (S. aureus) infections are often difficult to cure completely. One of
the main reasons for this difficulty is that S. aureus can be internalized into cells after …
the main reasons for this difficulty is that S. aureus can be internalized into cells after …
An Enzybiotic Regimen for the Treatment of Methicillin-Resistant Staphylococcus aureus Orthopaedic Device-Related Infection
ET Sumrall, MI Hofstee, D Arens, C Röhrig, S Baertl… - Antibiotics, 2021 - mdpi.com
Orthopaedic device-related infection (ODRI) presents a significant challenge to the field of
orthopaedic and trauma surgery. Despite extensive treatment involving surgical …
orthopaedic and trauma surgery. Despite extensive treatment involving surgical …
Measurement of Accumulation of Antibiotics to Staphylococcus aureus in Phagosomes of Live Macrophages**
JJ Kelly, BE Dalesandro, Z Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
Staphylococcus aureus (S. aureus) has evolved the ability to persist after uptake into host
immune cells. This intracellular niche enables S. aureus to potentially escape host immune …
immune cells. This intracellular niche enables S. aureus to potentially escape host immune …
Intracellular bacterial targeting by a thiazolyl benzenesulfonamide and octaarginine peptide complex
A brominated thiazolyl benzenesulfonamide (BTB) derivative is conjugated with the cell-
penetrating peptide octaarginine (R8) in an effort to construct innovative antibacterial …
penetrating peptide octaarginine (R8) in an effort to construct innovative antibacterial …
Antimicrobial bombinin-like peptide 3 selectively recognizes and inserts into bacterial biomimetic bilayers in multiple steps
Bombinins are a wide family of antimicrobial peptides from Xenopus skin. By sequence
clustering, we highlighted at least three families named A, B, and H, which might exert …
clustering, we highlighted at least three families named A, B, and H, which might exert …