Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula
L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …
systems biology theory, biological system network analysis, and multi-target drug molecule …
Machine learning approaches and databases for prediction of drug–target interaction: a survey paper
The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …
process of drug discovery. There is a need to develop novel and efficient prediction …
The IntAct database: efficient access to fine-grained molecular interaction data
N Del Toro, A Shrivastava, E Ragueneau… - Nucleic acids …, 2022 - academic.oup.com
The IntAct molecular interaction database (https://www. ebi. ac. uk/intact) is a curated
resource of molecular interactions, derived from the scientific literature and from direct data …
resource of molecular interactions, derived from the scientific literature and from direct data …
CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
Cell–cell communication mediated by ligand–receptor complexes is critical to coordinating
diverse biological processes, such as development, differentiation and inflammation. To …
diverse biological processes, such as development, differentiation and inflammation. To …
Network medicine framework for identifying drug-repurposing opportunities for COVID-19
The COVID-19 pandemic has highlighted the need to quickly and reliably prioritize clinically
approved compounds for their potential effectiveness for severe acute respiratory syndrome …
approved compounds for their potential effectiveness for severe acute respiratory syndrome …
A reference map of the human binary protein interactome
Global insights into cellular organization and genome function require comprehensive
understanding of the interactome networks that mediate genotype–phenotype relationships …
understanding of the interactome networks that mediate genotype–phenotype relationships …
Architecture of the human interactome defines protein communities and disease networks
The physiology of a cell can be viewed as the product of thousands of proteins acting in
concert to shape the cellular response. Coordination is achieved in part through networks of …
concert to shape the cellular response. Coordination is achieved in part through networks of …
Modeling protein quaternary structure of homo-and hetero-oligomers beyond binary interactions by homology
Cellular processes often depend on interactions between proteins and the formation of
macromolecular complexes. The impairment of such interactions can lead to deregulation of …
macromolecular complexes. The impairment of such interactions can lead to deregulation of …
[HTML][HTML] A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …
Network pharmacology to unveil the mechanism of Moluodan in the treatment of chronic atrophic gastritis
W Zhou, H Zhang, X Wang, J Kang, W Guo, L Zhou… - Phytomedicine, 2022 - Elsevier
Background Moluodan (MLD) is a traditional Chinese patent medicine for the treatment of
chronic atrophic gastritis (CAG). However, the mechanism of action (MoA) of MLD for …
chronic atrophic gastritis (CAG). However, the mechanism of action (MoA) of MLD for …