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Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
Bursting microbubbles: How nanobubble contrast agents can enable the future of medical ultrasound molecular imaging and image-guided therapy
The field of medical ultrasound has undergone a significant evolution since the development
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …
Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations
The problem of attenuation and sound speed of bubbly media has remained partially
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …
Toward precisely controllable acoustic response of shell-stabilized nanobubbles: High yield and narrow dispersity
Understanding the pressure dependence of the nonlinear behavior of ultrasonically excited
phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure …
phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure …
Efficient ultrasound-mediated drug delivery to orthotopic liver tumors–direct comparison of doxorubicin-loaded nanobubbles and microbubbles
Liver metastasis is a major obstacle in treating aggressive cancers, and current therapeutic
options often prove insufficient. To overcome these challenges, there has been growing …
options often prove insufficient. To overcome these challenges, there has been growing …
[HTML][HTML] Bubble-based drug delivery systems: Next-generation diagnosis to therapy
M Kancheva, L Aronson, T Pattilachan, F Sautto… - Journal of Functional …, 2023 - mdpi.com
Current radiologic and medication administration is systematic and has widespread side
effects; however, the administration of microbubbles and nanobubbles (MNBs) has the …
effects; however, the administration of microbubbles and nanobubbles (MNBs) has the …
[HTML][HTML] Influence of the liquid ionic strength on the resonance frequency and shell parameters of lipid-coated microbubbles
The correct measurement of the resonance frequency and shell properties of coated
microbubbles (MBs) is essential in understanding and optimizing their response to …
microbubbles (MBs) is essential in understanding and optimizing their response to …
High throughput microfluidic nanobubble generation by microporous membrane integration and controlled bubble shrinkage
Microfluidics has recently been proposed as a viable method for producing bulk
nanobubbles for use in various applications. The portability, compact size, and capacity to …
nanobubbles for use in various applications. The portability, compact size, and capacity to …
Super-resolved microbubble localization in single-channel ultrasound RF signals using deep learning
Recently, super-resolution ultrasound imaging with ultrasound localization microscopy
(ULM) has received much attention. However, ULM relies on low concentrations of …
(ULM) has received much attention. However, ULM relies on low concentrations of …
Buckling of lipidic ultrasound contrast agents under quasi-static load
G Chabouh, B van Elburg… - … of the Royal …, 2023 - royalsocietypublishing.org
Collapse of lipidic ultrasound contrast agents under high-frequency compressive load has
been historically interpreted by the vanishing of surface tension. By contrast, buckling of …
been historically interpreted by the vanishing of surface tension. By contrast, buckling of …