Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …

To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Hepatocytes are the main workers in the hepatic factory, managing metabolism of nutrients
and xenobiotics, production and recycling of proteins, and glucose and lipid homeostasis …

BACKGROUND Life-forms ranging from bacteria to humans are programmed by circadian
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …

Background: The circadian timing system or circadian clock plays a crucial role in many
biological processes, such as the sleep-wake cycle, hormone secretion, cardiovascular …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Temporal organization of physiology is critical for human health. In the past, humans
experienced predictable periods of daily light and dark driven by the solar day, which …

Circadian clocks coordinate physiology and behavior with the 24h solar day to provide
temporal homeostasis with the external environment. The molecular clocks that drive these …

Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

Circadian rhythms evolved through adaptation to daily light/dark changes in the
environment; they are believed to be regulated by the core circadian clock interlocking …