It's Not Easy Being Green: A Narrative Review on the Microbiology, Virulence and Therapeutic Prospects of Multidrug-Resistant Pseudomonas aeruginosa

P Behzadi, Z Baráth, M Gajdács - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is the most frequent cause of infection among non-fermenting
Gram-negative bacteria, predominantly affecting immunocompromised patients, but its …

Updates on the pathogenicity status of Pseudomonas aeruginosa

MW Azam, AU Khan - Drug discovery today, 2019 - Elsevier
Highlights•MDR P. aeruginosa is one of the major causes of the nosocomial
infections.•Virulence factors involved in pathogenicity were described.•Potential inhibitors of …

No Correlation between Biofilm Formation, Virulence Factors, and Antibiotic Resistance in Pseudomonas aeruginosa: Results from a Laboratory-Based In Vitro Study

M Gajdács, Z Baráth, K Kárpáti, D Szabó, D Usai… - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa (P. aeruginosa) possesses a plethora of virulence determinants,
including the production of biofilm, pigments, exotoxins, proteases, flagella, and secretion …

Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal …

J Luo, B Dong, K Wang, S Cai, T Liu, X Cheng, D Lei… - PloS one, 2017 - journals.plos.org
The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling
virulence factors and biofilm formation in Pseudomonas aeruginosa. QS-controlled biofilm …

Hordenine: A Novel Quorum Sensing Inhibitor and Antibiofilm Agent against Pseudomonas aeruginosa

JW Zhou, HZ Luo, H Jiang, TK Jian… - Journal of agricultural …, 2018 - ACS Publications
The quorum sensing (QS) inhibitory activity of hordenine from sprouting barley against
foodborne pathogen Pseudomonas aeruginosa was evaluated for the first time here. At …

Prevalence of different virulence factors and their association with antimicrobial resistance among Pseudomonas aeruginosa clinical isolates from Egypt

EA Edward, MR El Shehawy, A Abouelfetouh… - BMC microbiology, 2023 - Springer
Background Emergence of multi-drug resistant Pseudomonas aeruginosa, coupled with the
pathogen's versatile virulence factors, lead to high morbidity and mortality rates. The current …

Ellagic Acid Derivatives from Terminalia chebula Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate Pseudomonas aeruginosa PAO1 …

S Sarabhai, P Sharma, N Capalash - PLoS one, 2013 - journals.plos.org
Background Burgeoning antibiotic resistance in Pseudomonas aeruginosa has necessitated
the development of anti pathogenic agents that can quench acylhomoserine lactone (AHL) …

Superior inhibition of virulence and biofilm formation of Pseudomonas aeruginosa PAO1 by phyto-synthesized silver nanoparticles through anti-quorum sensing …

S Kumar, BS Paliya, BN Singh - Microbial Pathogenesis, 2022 - Elsevier
Quorum sensing (QS)-regulated bacterial biofilm formation is a crucial issue in causing
resistance against existing antibiotics. There is a considerable necessity to disrupt the …

Anti-quorum sensing and anti-biofilm activity of Delftia tsuruhatensis extract by attenuating the quorum sensing-controlled virulence factor production in Pseudomonas …

VK Singh, A Mishra, B Jha - Frontiers in cellular and infection …, 2017 - frontiersin.org
Multidrug-resistance bacteria commonly use cell-to-cell communication that leads to biofilm
formation as one of the mechanisms for develo** resistance. Quorum sensing inhibition …

Protein acetylation and its role in bacterial virulence

J Ren, Y Sang, J Lu, YF Yao - Trends in microbiology, 2017 - cell.com
Protein acetylation is a universal post-translational modification which is found in both
eukaryotes and prokaryotes. This process is achieved enzymatically by the protein …