Raman techniques: fundamentals and frontiers

RR Jones, DC Hooper, L Zhang, D Wolverson… - Nanoscale research …, 2019 - Springer
Driven by applications in chemical sensing, biological imaging and material
characterisation, Raman spectroscopies are attracting growing interest from a variety of …

[HTML][HTML] Recent developments and advances of femtosecond laser ablation: Towards image-guided microsurgery probes

M Calvarese, T Meyer-Zedler, M Schmitt… - TrAC Trends in …, 2023 - Elsevier
In this contribution we review recent developments and advances in femtosecond laser
ablation, with a focus on biomedical applications. In recent years, research has focused on …

Raman spectroscopy and imaging in bioanalytics

D Cialla-May, C Krafft, P Rösch… - Analytical …, 2021 - ACS Publications
Since the discovery of the inelastic scattering of light, ie, the so-called Raman effect, 1
Raman spectroscopy has become an attractive tool in a high number of research fields …

Multimodal nonlinear endomicroscopic imaging probe using a double-core double-clad fiber and focus-combining micro-optical concept

E Pshenay-Severin, H Bae, K Reichwald… - Light: Science & …, 2021 - nature.com
Multimodal non-linear microscopy combining coherent anti-Stokes Raman scattering,
second harmonic generation, and two-photon excited fluorescence has proved to be a …

Rise of Raman spectroscopy in neurosurgery: a review

D DePaoli, É Lemoine, K Ember… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: Although the clinical potential for Raman spectroscopy (RS) has been
anticipated for decades, it has only recently been used in neurosurgery. Still, few devices …

Opportunities of optical and spectral technologies in intraoperative histopathology

C Krafft, J Popp - Optica, 2023 - opg.optica.org
Modern optical and spectral technologies represent powerful approaches for a molecular
characterization of tissues enabling delineating pathological tissues but also a label-free …

Endomicroscopic AI-driven morphochemical imaging and fs-laser ablation for selective tumor identification and selective tissue removal

M Calvarese, E Corbetta, J Contreras, H Bae, C Lai… - Science …, 2024 - science.org
The rising incidence of head and neck cancer represents a serious global health challenge,
requiring more accurate diagnosis and innovative surgical approaches. Multimodal …

Biophotonic technologies for assessment of breast tumor surgical margins—A review

G Balasundaram, C Krafft, R Zhang, K Dev… - Journal of …, 2021 - Wiley Online Library
Breast conserving surgery (BCS) offering similar surgical outcomes as mastectomy while
retaining breast cosmesis is becoming increasingly popular for the management of early …

Feasibility studies of multimodal nonlinear endoscopy using multicore fiber bundles for remote scanning from tissue sections to bulk organs

H Bae, M Rodewald, T Meyer-Zedler, TW Bocklitz… - Scientific Reports, 2023 - nature.com
Here, we report on the development and application of a compact multi-core fiber optical
probe for multimodal non-linear imaging, combining the label-free modalities of Coherent …

Design and test of a rigid endomicroscopic system for multimodal imaging and femtosecond laser ablation

C Lai, M Calvarese, K Reichwald… - Journal of …, 2023 - spiedigitallibrary.org
Significance Conventional diagnosis of laryngeal cancer is normally made by a combination
of endoscopic examination, a subsequent biopsy, and histopathology, but this requires …