The potential anti-arrhythmic effect of SGLT2 inhibitors

HY Duan, H Barajas-Martinez, C Antzelevitch… - Cardiovascular …, 2024 - Springer
Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) were initially recommended as oral
anti-diabetic drugs to treat type 2 diabetes (T2D), by inhibiting SGLT2 in proximal tubule and …

[HTML][HTML] The Role of Sodium Glucose Co-Transporter 2 Inhibitors in Atrial Fibrillation: A Comprehensive Review

P Stachteas, A Nasoufidou, E Karagiannidis… - Journal of Clinical …, 2024 - mdpi.com
Atrial fibrillation (AF) is the most prevalent arrhythmia among adults worldwide, frequently co-
occurring with comorbidities such as Heart Failure (HF) and Type 2 Diabetes Mellitus …

SGLT2i effect on atrial fibrillation: A network meta‐analysis of randomized controlled trials

MV Mariani, G Manzi, N Pierucci… - Journal of …, 2024 - Wiley Online Library
Introduction Gliflozins are recommended as first‐line treatment in patients with heart failure
and/or cardiovascular comorbidities and are demonstrated to reduce atrial fibrillation (AF) …

Emerging role of antidiabetic drugs in cardiorenal protection

WJ Fu, JL Huo, ZH Mao, SK Pan, DW Liu… - Frontiers in …, 2024 - frontiersin.org
The global prevalence of diabetes mellitus (DM) has led to widespread multi-system
damage, especially in cardiovascular and renal functions, heightening morbidity and …

Sodium–glucose cotransporter 2 inhibitors and the cancer patient: from diabetes to cardioprotection and beyond

M Camilli, M Viscovo, L Maggio, A Bonanni… - Basic Research in …, 2024 - Springer
Sodium–glucose cotransporter 2 inhibitors (SGLT2i), a new drug class initially designed and
approved for treatment of diabetes mellitus, have been shown to exert pleiotropic metabolic …

Mitral regurgitation in heart failure with preserved ejection fraction: The interplay of valve, ventricle, and atrium

S Dhont, G van den Acker, T van Loon… - European journal of …, 2024 - Wiley Online Library
Mitral regurgitation (MR) is highly prevalent among patients with heart failure and preserved
ejection fraction (HFpEF). Despite this combination being closely associated with …

GLP-1 receptor agonists among patients with overweight or obesity, diabetes, and HFpEF on SGLT2 inhibitors

R Patel, M Wadid, B Makwana, A Kumar, S Khadke… - Heart Failure, 2024 - jacc.org
Background Although the use of glucagon-like peptide-1 receptor agonist (GLP-1 RA) in
patients with obesity and heart failure with preserved ejection fraction (HFpEF) has …

Glucagon-Like Peptide-1 Receptor Agonists and Atrial Fibrillation Recurrence After Ablation: A Fire Without the Smoke?

P Karakasis, D Patoulias, S Tzeis, N Fragakis - Clinical Electrophysiology, 2024 - jacc.org
We perused with heightened interest the study by Satti et al 1 in this issue of JACC: Clinical
Electrophysiology. The investigators leveraged data from the TriNetX research database to …

SGLT2 inhibitors and the cardiac rhythm: unraveling the connections

A Paul, C Tabaja, O Wazni - International Journal of Arrhythmia, 2024 - Springer
Sodium-glucose co-transporter 2 inhibitors (SGLT2is), primarily used for managing type 2
diabetes mellitus, have recently gained attention for their potential cardiovascular benefits …

Efficacy of dapagliflozin in improving arrhythmia-related outcomes after ablation for atrial fibrillation: a retrospective single-center study

HJ Noh, SJ Cha, CH Kim, SW Choi, CH Lee… - Clinical Research in …, 2024 - Springer
Background Atrial fibrillation (AF) is a widespread type of sustained arrhythmia that poses
significant health risks. Catheter ablation is the preferred treatment; however, arrhythmia …