Classification, ontology, and precision medicine

MA Haendel, CG Chute… - New England Journal of …, 2018‏ - Mass Medical Soc
Ontologies, Phenotypes, and Big Data Data-organizing methods have been in place for
centuries, but very large data sets have come into being relatively recently. The authors …

The immune epitope database (IEDB): 2018 update

R Vita, S Mahajan, JA Overton, SK Dhanda… - Nucleic acids …, 2019‏ - academic.oup.com
Abstract The Immune Epitope Database (IEDB, iedb. org) captures experimental data
confined in figures, text and tables of the scientific literature, making it freely available and …

Current challenges and recent advances on the path towards continuous biomanufacturing

M Drobnjakovic, R Hart, B Kulvatunyou… - Biotechnology …, 2023‏ - Wiley Online Library
Continuous biopharmaceutical manufacturing is currently a field of intense research due to
its potential to make the entire production process more optimal for the modern, ever …

Human Disease Ontology 2018 update: classification, content and workflow expansion

LM Schriml, E Mitraka, J Munro, B Tauber… - Nucleic acids …, 2019‏ - academic.oup.com
Abstract The Human Disease Ontology (DO)(http://www. disease-ontology. org), database
has undergone significant expansion in the past three years. The DO disease classification …

BFO: Basic formal ontology

JN Otte, J Beverley, A Ruttenberg - Applied ontology, 2022‏ - journals.sagepub.com
Basic Formal Ontology (BFO) is a top-level ontology consisting of thirty-six classes, designed
to support information integration, retrieval, and analysis across all domains of scientific …

The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species

CJ Mungall, JA McMurry, S Köhler… - Nucleic acids …, 2017‏ - academic.oup.com
The correlation of phenotypic outcomes with genetic variation and environmental factors is a
core pursuit in biology and biomedicine. Numerous challenges impede our progress: patient …

CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis

Y He, H Yu, E Ong, Y Wang, Y Liu, A Huffman… - Scientific data, 2020‏ - nature.com
CIDO, a community-based ontology for coronavirus disease knowledge and data integration,
sharing, and analysis | Scientific Data Skip to main content Thank you for visiting nature.com …

SigCom LINCS: data and metadata search engine for a million gene expression signatures

JE Evangelista, DJB Clarke, Z **e… - Nucleic acids …, 2022‏ - academic.oup.com
Millions of transcriptome samples were generated by the Library of Integrated Network-
based Cellular Signatures (LINCS) program. When these data are processed into …

ROBOT: a tool for automating ontology workflows

RC Jackson, JP Balhoff, E Douglass, NL Harris… - BMC …, 2019‏ - Springer
Background Ontologies are invaluable in the life sciences, but building and maintaining
ontologies often requires a challenging number of distinct tasks such as running automated …

Representation of behaviour change interventions and their evaluation: Development of the Upper Level of the Behaviour Change Intervention Ontology

S Michie, R West, AN Finnerty, E Norris… - Wellcome open …, 2021‏ - pmc.ncbi.nlm.nih.gov
Background: Behaviour change interventions (BCI), their contexts and evaluation methods
are heterogeneous, making it difficult to synthesise evidence and make recommendations …