Autophagy is a dynamic process by which intracellular damaged macromolecules and
organelles are degraded and recycled for the synthesis of new cellular components. Basal …

Lithium is most well-known for its mood-stabilizing effects in the treatment of bipolar
disorder. Due to its narrow therapeutic window (0.5-1.2 mM serum concentration), there is a …

Organoid technology is rapidly gaining ground for studies on organ (patho) physiology.
Tubuloids are long-term expanding organoids grown from adult kidney tissue or urine. The …

Perioperative organ injury remains a medical, social and economic problem in cardiac
surgery. Patients with postoperative organ dysfunction have increases in morbidity, length of …

Trace amounts of lithium are essential for our physical and mental health, and administration
of lithium has improved the quality of life of millions of patients with bipolar disorder for> 60 …

Introduction Renal cell cancer (RCC) syndrome is linked to Krebs cycle compartments and
their coding genes' alterations like succinate dehydrogenase genes (SDHx). Here we …

While lithium remains the most efficacious treatment for bipolar disorder, it can cause
significant nephrotoxicity. The molecular mechanisms behind both this process and the …

Islet inflammation is associated with defective β cell function and mass in type 2 diabetes
(T2D). Glycogen Synthase Kinase 3β (GSK3β) has been identified as an important regulator …

Objective To explore the effect of erythropoietin (EPO) on the AMP-activated protein kinase
(AMPK)/nicotinamide adenine dinucleotide phosphatase oxidase 4 (NOX4) signaling …

Lithium has long been widely used in the treatment of bipolar mood disorders. Recent
studies have demonstrated that lithium is able to decrease ischemia/reperfusion (I/R) injury …