Glycosylation is one of the most common, and the most complex, forms of post‐translational
modification of proteins. This review serves to highlight the role of protein glycosylation in …

A common feature in the Alzheimer's disease (AD) brain is the presence of
acetylcholinesterase (AChE) which is commonly associated with β-amyloid plaques and …

Almost all therapeutic proteins are glycosylated, with the carbohydrate component playing a
long-established, substantial role in the safety and pharmacokinetic properties of this …

The link between histopathological hallmarks of Alzheimer's disease (AD), ie amyloid
plaques, and neurofibrillary tangles, and AD-associated cognitive impairment, has long …

The global burden of Alzheimer's disease (AD) is growing. Valiant efforts to develop clinical
candidates for treatment have continuously met with failure. Currently available palliative …

Protein glycosylation regulates protein function and cellular distribution. Additionally,
aberrant protein glycosylations have been recognized to play major roles in human …

Post-translational modifications (PTMs) can occur soon after translation or at any stage in
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …

Traumatic brain injuries (TBIs) present a chief public health threat affecting nations
worldwide. As numbers of patients afflicted by TBI are expected to rise, the necessity to …

The amyloid precursor protein (APP), presenilin 1 (PS1), amyloid beta (Aβ), and GSK3 are
the effectors, which are significantly associated with progression of Alzheimer's Disease …

Abstract Analysis of the expressed protein complement of cells requires knowledge of the
diversity of post‐translational modifications that can occur and which can be transient or …