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Visible-light-responsive novel Ru (II)-metallo-antibiotics with potential antibiofilm and antibacterial activity
Growing challenges with antibiotic resistance pose immense challenges in combating
microbial infections and biofilm prevention on medical devices. Lately, antibacterial …
microbial infections and biofilm prevention on medical devices. Lately, antibacterial …
Green Light-Triggered Photocatalytic Anticancer Activity of Terpyridine-Based Ru (II) Photocatalysts
The relentless increase in drug resistance of platinum-based chemotherapeutics has
opened the scope for other new cancer therapies with novel mechanisms of action (MoA) …
opened the scope for other new cancer therapies with novel mechanisms of action (MoA) …
Photodynamic therapy photosensitizers and photoactivated chemotherapeutics exhibit distinct bioenergetic profiles to impact ATP metabolism
Energy is essential for all life, and mammalian cells generate and store energy in the form of
ATP by mitochondrial (oxidative phosphorylation) and non-mitochondrial (glycolysis) …
ATP by mitochondrial (oxidative phosphorylation) and non-mitochondrial (glycolysis) …
Comparison of click-capable oxaliplatin and cisplatin derivatives to better understand Pt (ii)-induced nucleolar stress
Pt (II) chemotherapeutic complexes have been used as predominant anticancer drugs for
nearly fifty years. Currently there are three FDA-approved chemotherapeutic Pt (II) …
nearly fifty years. Currently there are three FDA-approved chemotherapeutic Pt (II) …
Click-capable phenanthriplatin derivatives as tools to study Pt (II)-Induced nucleolar stress
It is well established that oxaliplatin, one of the three Pt (II) anticancer drugs approved
worldwide, and phenanthriplatin, an important preclinical monofunctional Pt (II) anticancer …
worldwide, and phenanthriplatin, an important preclinical monofunctional Pt (II) anticancer …