The metabolic roots of senescence: mechanisms and opportunities for intervention
CD Wiley, J Campisi - Nature Metabolism, 2021 - nature.com
Cellular senescence entails a permanent proliferative arrest, coupled to multiple phenotypic
changes. Among these changes is the release of numerous biologically active molecules …
changes. Among these changes is the release of numerous biologically active molecules …
Neuroprotective effect of antioxidants in the brain
KH Lee, M Cha, BH Lee - International journal of molecular sciences, 2020 - mdpi.com
The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …
Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism
A number of studies have reported that zinc plays a substantial role in the development of
metabolic syndrome, taking part in the regulation of cytokine expression, suppressing …
metabolic syndrome, taking part in the regulation of cytokine expression, suppressing …
Role of zinc in immune system and anti-cancer defense mechanisms
D Skrajnowska, B Bobrowska-Korczak - Nutrients, 2019 - mdpi.com
The human body cannot store zinc reserves, so a deficiency can arise relatively quickly, eg,
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …
[HTML][HTML] The role of metallothionein in oxidative stress
Free radicals are chemical particles containing one or more unpaired electrons, which may
be part of the molecule. They cause the molecule to become highly reactive. The free …
be part of the molecule. They cause the molecule to become highly reactive. The free …
[HTML][HTML] Zinc and oxidative stress: current mechanisms
DN Marreiro, KJC Cruz, JBS Morais, JB Beserra… - Antioxidants, 2017 - mdpi.com
Oxidative stress is a metabolic dysfunction that favors the oxidation of biomolecules,
contributing to the oxidative damage of cells and tissues. This consequently contributes to …
contributing to the oxidative damage of cells and tissues. This consequently contributes to …
Atomic structure of the entire mammalian mitochondrial complex I
Mitochondrial complex I (also known as NADH: ubiquinone oxidoreductase) contributes to
cellular energy production by transferring electrons from NADH to ubiquinone coupled to …
cellular energy production by transferring electrons from NADH to ubiquinone coupled to …
Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases
S Choi, X Liu, Z Pan - Acta Pharmacologica Sinica, 2018 - nature.com
Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …
inflammatory functions. The association between zinc deficiency and the development of …
Exploring the potential function of trace elements in human health: a therapeutic perspective
A trace element, known as a minor element, is a chemical element whose concentration is
very low. They are divided into essential and non-essential classes. Numerous physiological …
very low. They are divided into essential and non-essential classes. Numerous physiological …
[HTML][HTML] Health position paper and redox perspectives-disease burden by transportation noise
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …