Abstract The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private–public
partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that …

Understanding how dietary nutrients modulate the gut microbiome is of great interest for the
development of food products and eating patterns for combatting the global burden of non …

The intestine and liver are thought to metabolize dietary nutrients and regulate host nutrient
homeostasis. Here, we find that the gut microbiota also reshapes the host amino acid (aa) …

Short-amplicon 16S rRNA gene sequencing is currently the method of choice for studies
investigating microbiomes. However, comparative studies on differences in procedures are …

Currently, there are no medications that effectively treat the core symptoms of Autism
Spectrum Disorder (ASD). We recently found that the bacterial species Lactobacillus (L.) …

Anti–PD-1–based immunotherapy has had a major impact on cancer treatment but has only
benefited a subset of patients. Among the variables that could contribute to interpatient …

In develo** countries, the use of antibiotics has helped to reduce the mortality rate by
minimizing the deaths caused by pathogenic infections, but the costs of antibiotic …

Reference genomes are essential for metagenomic analyses and functional characterization
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …

The gastrointestinal tract of mammals hosts a high and diverse number of different
microorganisms, known as intestinal microbiota. Many probiotics were originally isolated …

Keystone taxa in ecological communities are native taxa that play an especially important
role in the stability of their ecosystem. However, we still lack an effective framework for …