Motor rehabilitation after stroke: European Stroke Organisation (ESO) consensus-based definition and guiding framework

G Kwakkel, C Stinear, B Essers… - European stroke …, 2023 - journals.sagepub.com
Purpose: To propose a consensus-based definition and framework for motor rehabilitation
after stroke. Methods: An expert European working group reviewed the literature, attaining …

Precision medicine in stroke: towards personalized outcome predictions using artificial intelligence

AK Bonkhoff, C Grefkes - Brain, 2022 - academic.oup.com
Stroke ranks among the leading causes for morbidity and mortality worldwide. New and
continuously improving treatment options such as thrombolysis and thrombectomy have …

Recovery from stroke: current concepts and future perspectives

C Grefkes, GR Fink - Neurological research and practice, 2020 - Springer
Stroke is a leading cause of acquired, permanent disability worldwide. Although the
treatment of acute stroke has been improved considerably, the majority of patients to date …

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

GJ Hankey, ML Hackett, OP Almeida, L Flicker… - The Lancet …, 2020 - thelancet.com
Background Trials of fluoxetine for recovery after stroke report conflicting results. The
Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral …

Evidence of rTMS for motor or cognitive stroke recovery: hype or hope?

J Hofmeijer, F Ham, G Kwakkel - Stroke, 2023 - ahajournals.org
BACKGROUND: Evidence of efficacy of repetitive transcranial magnetic stimulation (rTMS)
for stroke recovery is hampered by an unexplained variability of reported effect sizes and an …

Extended reality to assess post-stroke manual dexterity: contrasts between the classic box and block test, immersive virtual reality with controllers, with hand-tracking …

G Everard, Q Burton, V Van de Sype… - Journal of …, 2024 - Springer
Background Recent technological advancements present promising opportunities to
enhance the frequency and objectivity of functional assessments, aligning with recent stroke …

eXplainable AI allows predicting upper limb rehabilitation outcomes in sub-acute stroke patients

M Gandolfi, IB Galazzo, RG Pavan… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
While stroke is one of the leading causes of disability, the prediction of upper limb (UL)
functional recovery following rehabilitation is still unsatisfactory, hampered by the clinical …

Upper limb performance in daily life approaches plateau around three to six weeks post-stroke

CE Lang, KJ Waddell, J Barth… - … and neural repair, 2021 - journals.sagepub.com
Background. Wearable sensors allow for direct measurement of upper limb (UL)
performance in daily life. Objective. To map the trajectory of UL performance and its …

Is recovery of somatosensory impairment conditional for upper-limb motor recovery early after stroke?

SB Zandvliet, G Kwakkel, RHM Nijland… - … and neural repair, 2020 - journals.sagepub.com
Background. Spontaneous recovery early after stroke is most evident during a time-sensitive
window of heightened neuroplasticity, known as spontaneous neurobiological recovery. It is …

Segmental motor recovery after cervical spinal cord injury relates to density and integrity of corticospinal tract projections

G Balbinot, G Li, S Kalsi-Ryan, R Abel, D Maier… - Nature …, 2023 - nature.com
Cervical spinal cord injury (SCI) causes extensive impairments for individuals which may
include dextrous hand function. Although prior work has focused on the recovery at the …