Intercellular mitochondrial transfer as a means of tissue revitalization

D Liu, Y Gao, J Liu, Y Huang, J Yin, Y Feng… - Signal transduction and …, 2021 - nature.com
As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion
frequently undergoes morphological or positional changes when responding to various …

Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction

S Phuyal, P Romani, S Dupont, H Farhan - Trends in Cell Biology, 2023 - cell.com
Mechanobiology studies the mechanisms by which cells sense and respond to physical
forces, and the role of these forces in sha** cells and tissues themselves …

Axonal endoplasmic reticulum dynamics and its roles in neurodegeneration

Z Öztürk, CJ O'Kane, JJ Pérez-Moreno - Frontiers in neuroscience, 2020 - frontiersin.org
The physical continuity of axons over long cellular distances poses challenges for their
maintenance. One organelle that faces this challenge is endoplasmic reticulum (ER); unlike …

Go with the flow–bulk transport by molecular motors

W Lu, VI Gelfand - Journal of cell science, 2023 - journals.biologists.com
Cells are the smallest building blocks of all living eukaryotic organisms, usually ranging from
a couple of micrometers (for example, platelets) to hundreds of micrometers (for example …

Structural response of microtubule and actin cytoskeletons to direct intracellular load

R Orii, H Tanimoto - Journal of Cell Biology, 2025 - rupress.org
Microtubule and actin are the two major cytoskeletal polymers that form organized functional
structures in the interior of eukaryotic cells. Although the structural mechanics of the …

Cytoplasmic stirring by active carpets

B Chakrabarti, M Rachh, SY Shvartsman… - Proceedings of the …, 2024 - pnas.org
Large cells often rely on cytoplasmic flows for intracellular transport, maintaining
homeostasis, and positioning cellular components. Understanding the mechanisms of these …

Patterning and polarization of cells by intracellular flows

R Illukkumbura, T Bland, NW Goehring - Current opinion in cell biology, 2020 - Elsevier
Beginning with Turing's seminal work [1], decades of research have demonstrated the
fundamental ability of biochemical networks to generate and sustain the formation of …

The role of spastin in axon biology

AC Costa, MM Sousa - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Neurons are highly polarized cells with elaborate shapes that allow them to perform their
function. In neurons, microtubule organization—length, density, and dynamics—are …

Swirling instability of the microtubule cytoskeleton

DB Stein, G De Canio, E Lauga, MJ Shelley… - Physical review …, 2021 - APS
In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along
a network of microtubules entrain the surrounding fluid. The piconewton forces produced by …

Cytoplasm's got moves

S Shamipour, S Caballero-Mancebo, CP Heisenberg - Developmental Cell, 2021 - cell.com
Cytoplasm is a gel-like crowded environment composed of various macromolecules,
organelles, cytoskeletal networks, and cytosol. The structure of the cytoplasm is highly …