Shedding light on neurons: optical approaches for neuromodulation

S Jiang, X Wu, NJ Rommelfanger, Z Ou… - National Science …, 2022 - academic.oup.com
Today's optical neuromodulation techniques are rapidly evolving, benefiting from advances
in photonics, genetics and materials science. In this review, we provide an up-to-date …

Chemogenetic modulation of astrocytes and microglia: State‐of‐the‐art and implications in neuroscience

J Bossuyt, Y Van Den Herrewegen, L Nestor, A Buckinx… - Glia, 2023 - Wiley Online Library
Insights into the role astrocytes and microglia play in normal and diseased brain functioning
has expanded drastically over the last decade. Recently, chemogenetic tools have emerged …

The lateralization of left hippocampal CA3 during the retrieval of spatial working memory

D Song, D Wang, Q Yang, T Yan, Z Wang, Y Yan… - Nature …, 2020 - nature.com
The hippocampal CA3 contributes to spatial working memory (SWM), but which stage of
SWM the CA3 neurons act on and whether the lateralization of CA3 function occurs in SWM …

[HTML][HTML] Bilateral optogenetic activation of inhibitory cells favors ictogenesis

M Lévesque, S Wang, G Etter, S Williams… - Neurobiology of Disease, 2022 - Elsevier
Mesial temporal lobe epilepsy (MTLE) is the most common type of focal refractory epilepsy
and is characterized by recurring seizures that are often refractory to medication. Since …

Chemogenetic rectification of the inhibitory tone onto hippocampal neurons reverts autistic-like traits and normalizes local expression of estrogen receptors in the …

A Pignataro, P Krashia, M De Introna, A Nobili… - Translational …, 2023 - nature.com
Female, but not male, mice with haploinsufficiency for the proautophagic Ambra1 gene show
an autistic-like phenotype associated with hippocampal circuits dysfunctions which include …

Botanicals as modulators of depression and mechanisms involved

Z Zhang, T Deng, M Wu, A Zhu, G Zhu - Chinese Medicine, 2019 - Springer
Depression is the most disastrous mood disorder affecting the health of individuals.
Conventional treatments with chemical compounds for depression have limitations, while …

An energy-efficient optically-enhanced highly-linear implantable wirelessly-powered bidirectional optogenetic neuro-stimulator

T Yousefi, M Taghadosi, A Dabbaghian… - … Circuits and Systems, 2020 - ieeexplore.ieee.org
This paper presents an energy-efficient mm-scale self-contained bidirectional optogenetic
neuro-stimulator, which employs a novel highly-linear μLED driving circuit architecture as …

[HTML][HTML] Optogenetic behavioral studies in depression research: A systematic review

A Spreen, D Alkhoury, H Walter, S Müller - Iscience, 2024 - cell.com
Optogenetics has made substantial contributions to our understanding of the mechanistic
underpinnings of depression. This systematic review employs quantitative analysis to …

[PDF][PDF] Spatial, temporal, and circuit-specific activation patterns of basolateral amygdala projection neurons during stress

R Aukema, G Petrie, A Matarasso, B Lau… - …, 2023 - prism.ucalgary.ca
Spatial, temporal, and circuit-specific activation patterns of basolateral amygdala projection
neurons during stress Page 1 University of Calgary PRISM Repository https://prism.ucalgary.ca …

Optogenetic recruitment of hypothalamic corticotrophin-releasing-hormone (CRH) neurons reduces motivational drive

CS Mitchell, EJ Campbell, SD Fisher… - Translational …, 2024 - nature.com
Impaired motivational drive is a key feature of depression. Chronic stress is a known
antecedent to the development of depression in humans and depressive-like states in …