Targeted imaging in atherosclerosis

J Li, K Wang, W Pan, N Li, B Tang - Analytical Chemistry, 2022 - ACS Publications
Atherosclerosis is a chronic inflammatory disease involved in plaque rupture, stroke,
thrombosis, and heart attack (myocardial infarction), which is a leading cause of sudden …

MR/PET imaging of the cardiovascular system

PM Robson, D Dey, DE Newby, D Berman, D Li… - JACC: Cardiovascular …, 2017 - jacc.org
Cardiovascular imaging has largely focused on identifying structural, functional, and
metabolic changes in the heart. The ability to reliably assess disease activity would have …

[68Ga] Pentixafor-PET/MRI for the detection of Chemokine receptor 4 expression in atherosclerotic plaques

X Li, D Heber, T Leike, D Beitzke, X Lu, X Zhang… - European Journal of …, 2018 - Springer
Purpose The expression of chemokine receptor type 4 (CXCR4) was found co-localized with
macrophages on the atherosclerotic vessel wall and participated in the initial emigration of …

Imaging inflammation in atherosclerosis with CXCR4-directed 68Ga-pentixafor PET/CT: correlation with 18F-FDG PET/CT

M Kircher, J Tran-Gia, L Kemmer, X Zhang… - Journal of Nuclear …, 2020 - Soc Nuclear Med
CXC motif chemokine receptor 4 (CXCR4) is expressed on the surface of various cell types
involved in atherosclerosis, with a particularly rich receptor expression on macrophages and …

Recent advances in molecular imaging of atherosclerotic plaques and thrombosis

R Qiao, X Huang, Y Qin, Y Li, TP Davis, CE Hagemeyer… - Nanoscale, 2020 - pubs.rsc.org
As the complications of atherosclerosis such as myocardial infarction and stroke are still one
of the leading causes of mortality worldwide, the development of new diagnostic tools for the …

18F-NaF PET/MRI for Detection of Carotid Atheroma in Acute Neurovascular Syndrome

J Kaczynski, S Sellers, MA Seidman, M Syed, M Dennis… - Radiology, 2022 - pubs.rsna.org
Background MRI and fluorine 18–labeled sodium fluoride (18F-NaF) PET can be used to
identify features of plaque instability, rupture, and disease activity, but large studies have not …

[68Ga]Pentixafor PET/MR imaging of chemokine receptor 4 expression in the human carotid artery

X Li, W Yu, T Wollenweber, X Lu, Y Wei… - European Journal of …, 2019 - Springer
Purpose Type 4 chemokine receptor (CXCR4) plays an important role in immune cell
migration during the atherosclerosis progression. We aimed to evaluate [68 Ga] Pentixafor …

Combined PET/MRI: from status quo to status go. Summary report of the fifth international workshop on PET/MR imaging; February 15–19, 2016; Tübingen, Germany

DL Bailey, BJ Pichler, B Gueckel, H Barthel… - Molecular imaging and …, 2016 - Springer
This article provides a collaborative perspective of the discussions and conclusions from the
fifth international workshop of combined positron emission tomorgraphy (PET)/magnetic …

Detection and imaging of active substances in early atherosclerotic lesions using fluorescent probes

J Li, J Xu, W Zhang, P Li, W Zhang, H Wang… - …, 2023 - Wiley Online Library
Atherosclerosis (AS) is a vascular disease caused by chronic inflammation and lipids that is
the main cause of myocardial infarction, stroke and other cardiovascular diseases …

Imaging Inflammation in Atherosclerosis with CXCR4-Directed [68Ga]PentixaFor PET/MRI—Compared with [18F]FDG PET/MRI

X Lu, R Calabretta, W Wadsak, AR Haug… - Life, 2022 - mdpi.com
(1) This study compared [68Ga] PentixaFor uptake in active arterial segments with
corresponding [18F] FDG arterial uptake as well as the relationship with cardiac [68Ga] …