Engineering cell metabolism for bioproduction not only consumes building blocks and
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …

Systems biology and synthetic biology are increasingly used to examine and modulate
complex biological systems. As such, many issues arising during scaling-up microbial …

Knowledge mining from synthetic biology journal articles for machine learning (ML)
applications is a labor-intensive process. The development of natural language processing …

Biosystems such as enzymes, pathways, and whole cells have been increasingly explored
for biotechnological applications. However, the intricate connectivity and resulting …

Global warming and decreasing fossil fuel reserves have prompted great interest in the
synthesis of advanced biofuels from renewable resources. In an effort to address these …

Terpenes are natural products with a remarkable diversity in their chemical structures and
they hold a significant market share commercially owing to their distinct applications. These …

Genome scale modeling (GSM) predicts the performance of microbial workhorses and helps
identify beneficial gene targets. GSM integrated with intracellular flux dynamics, omics, and …

Engineered yeast are an important production platform for the biosynthesis of high-value
compounds with medical applications. Recent years have witnessed several new …

Synthetic biology and metabolic engineering enable generation of novel cell factories that
efficiently convert renewable feedstocks into biofuels, bulk, and fine chemicals, thus creating …

Traditionally, high-value metabolites have been produced through direct extraction from
natural biological sources which are inefficient, given the low abundance of these …