As information flows through the brain, neuronal firing progresses from encoding the world
as sensed by the animal to driving the motor output of subsequent behavior. One of the more …

Neural systems adapt to changes in stimulus statistics. However, it is not known how stimuli
with complex temporal dynamics drive the dynamics of adaptation and the resulting firing …

Insect proprioception utilizes hundreds of campaniform sensilla embedded in the
exoskeleton that sense strain. These sensilla are essential for many behaviors, especially …

Perineuronal nets (PNNs) are specialized complexes of extracellular matrix molecules that
surround the somata of fast-spiking neurons throughout the vertebrate brain. PNNs are …

Neurons transform time-varying inputs into action potentials emitted stochastically at a time
dependent rate. The map** from current input to output firing rate is often represented with …

Neuronal responses to ongoing stimulation in many systems change over time, or “adapt.”
Despite the ubiquity of adaptation, its effects on the stimulus information carried by neurons …

Neural networks are more than the sum of their parts, but the properties of those parts are
nonetheless important. For instance, neuronal properties affect the degree to which neurons …

Cell-to-cell variability in molecular, genetic, and physiological features is increasingly
recognized as a critical feature of complex biological systems, including the brain. Although …

Biophysically accurate multicompartmental models of individual neurons have significantly
advanced our understanding of the input–output function of single cells. These models …

Cortical receptive fields represent the signal preferences of sensory neurons. Receptive
fields are thought to provide a representation of sensory experience from which the cerebral …