The multimodality cell segmentation challenge: toward universal solutions

J Ma, R **e, S Ayyadhury, C Ge, A Gupta, R Gupta… - Nature …, 2024 - nature.com
Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images.
Existing cell segmentation methods are often tailored to specific modalities or require …

Machine learning for cross-scale microscopy of viruses

A Petkidis, V Andriasyan, UF Greber - Cell Reports Methods, 2023 - cell.com
Despite advances in virological sciences and antiviral research, viruses continue to emerge,
circulate, and threaten public health. We still lack a comprehensive understanding of how …

NuInsSeg: A fully annotated dataset for nuclei instance segmentation in H&E-stained histological images

A Mahbod, C Polak, K Feldmann, R Khan, K Gelles… - Scientific Data, 2024 - nature.com
In computational pathology, automatic nuclei instance segmentation plays an essential role
in whole slide image analysis. While many computerized approaches have been proposed …

A survey on cell nuclei instance segmentation and classification: Leveraging context and attention

JD Nunes, D Montezuma, D Oliveira, T Pereira… - Medical Image …, 2024 - Elsevier
Nuclear-derived morphological features and biomarkers provide relevant insights regarding
the tumour microenvironment, while also allowing diagnosis and prognosis in specific …

Domain generalization in computational pathology: survey and guidelines

M Jahanifar, M Raza, K Xu, T Vuong… - arxiv preprint arxiv …, 2023 - arxiv.org
Deep learning models have exhibited exceptional effectiveness in Computational Pathology
(CPath) by tackling intricate tasks across an array of histology image analysis applications …

DAWN: Domain-Adaptive Weakly Supervised Nuclei Segmentation via Cross-Task Interactions

Y Zhang, Y Wang, Z Fang, H Bian, L Cai… - arxiv preprint arxiv …, 2024 - arxiv.org
Weakly supervised segmentation methods have gained significant attention due to their
ability to reduce the reliance on costly pixel-level annotations during model training …

Deep learning for predicting prognostic consensus molecular subtypes in cervical cancer from histology images

R Wang, GN Gunesli, VE Skingen, KAF Valen… - npj Precision …, 2025 - nature.com
Cervical cancer remains the fourth most common cancer among women worldwide. This
study proposes an end-to-end deep learning framework to predict consensus molecular …

GrandQC: A comprehensive solution to quality control problem in digital pathology

Z Weng, A Seper, A Pryalukhin, F Mairinger… - Nature …, 2024 - nature.com
Histological slides contain numerous artifacts that can significantly deteriorate the
performance of image analysis algorithms. Here we develop the GrandQC tool for tissue and …

A novel AI-based score for assessing the prognostic value of intra-epithelial lymphocytes in oral epithelial dysplasia

AJ Shephard, H Mahmood, SEA Raza… - British Journal of …, 2024 - nature.com
Background Oral epithelial dysplasia (OED) poses a significant clinical challenge due to its
potential for malignant transformation and the lack of reliable prognostic markers. Current …

An automated pipeline for tumour-infiltrating lymphocyte scoring in breast cancer

AJ Shephard, M Jahanifar, R Wang… - 2024 IEEE …, 2024 - ieeexplore.ieee.org
Tumour-infiltrating lymphocytes (TILs) are considered as a valuable prognostic markers in
both triple-negative and human epidermal growth factor receptor 2 (HER2) positive breast …