Insomnia poses significant challenges to public health. It is a common condition associated
with marked impairment in function and quality of life, psychiatric and physical morbidity, and …

The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

The pathophysiology of affective disorders—particularly circuit-level mechanisms underlying
bidirectional, periodic affective state transitions—remains poorly understood. In patients …

Objective: To determine if a treatment for interepisode bipolar disorder I patients with
insomnia improves mood state, sleep, and functioning. Method: Alongside psychiatric care …

Despite advances in the treatment of bipolar disorder, a significant proportion of patients
experience disabling symptoms between episodes, and relapse rates are high. These …

Background Whilst cannabis use appears to be a causal risk factor for the development of
schizophrenia-related psychosis, associations with mania remain relatively unknown. This …

Objective: To determine if the Transdiagnostic Intervention for Sleep and Circadian
Dysfunction (TranS-C) improves functional impairment, psychiatric symptoms, and sleep and …

Insomnia is a pervasive problem for many patients suffering from medical and psychiatric
conditions. Even when the comorbid disorders are successfully treated, insomnia often fails …

Objectives. These guidelines are based on a first edition that was published in 2002, and
have been edited and updated with the available scientific evidence until September 2009 …

This paper reviews evidence for deficits in goal regulation in bipolar disorder. A series of
authors have described mania as related to higher accomplishment, elevated achievement …