Congenital hearing loss (hearing loss that is present at birth) is one of the most prevalent
chronic conditions in children. In the majority of developed countries, neonatal hearing …

Programmed cell death (PCD)—apoptosis, autophagy and programmed necrosis—is any
pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing …

Although genetic factors contribute to almost half of all cases of deafness, treatment options
for genetic deafness are limited,,,,. We developed a genome-editing approach to target a …

How does a room affect an occupant's behavior and well-being? How does a building
influence its residents' health? Environmental Psychology for Design, 3rd Edition, explores …

Hearing loss is the most common sensory deficit in humans, affecting 1 in 500 newborns.
Due to its genetic heterogeneity, comprehensive diagnostic testing has not previously been …

Due to the high genetic heterogeneity of hearing loss (HL), current clinical testing includes
sequencing large numbers of genes, which often yields a significant number of novel …

Prelingual non-syndromic (isolated) deafness is the most frequent hereditary sensory defect.
In> 80% of the cases, the mode of transmission is autosomal recessive. To date, 14 loci …

Hearing impairment is the most commonly occurring condition that affects the ability of
humans to communicate 1. More than 50% of the cases of profound early-onset deafness …

Despite the enormous heterogeneity of genetic hearing loss, variants in one locus, Gap
Junction Beta 2 or GJB2 (connexin 26), account for up to 50% of cases of nonsyndromic …

Hearing loss is a common and complex condition that can occur at any age, can be inherited
or acquired, and is associated with a remarkably wide array of etiologies. The diverse …