Many psychiatric illnesses are associated with early mortality and with an increased risk of
develo** physical diseases that are more typically seen in the elderly. Moreover, certain …

Objective This study examined the relationship between leukocyte telomere length (LTL), a
marker of cell aging, and psychiatric disorders in adults compared with controls using meta …

Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

Increased peripheral levels of morning cortisol have been reported in people with
schizophrenia (SZ) and bipolar disorder (BD), but findings are inconsistent and few studies …

Schizophrenia (SZ) is a brain disorder that has been intensively studied for over a century;
yet, its etiology and multifactorial pathophysiology remain a puzzle. However, significant …

Telomeres play an important part in aging and show relationships to lifetime adversity,
particularly childhood adversity. Meta-analyses demonstrate reliable associations between …

Background: Schizophrenia is associated with increased physical morbidity and early
mortality, suggesting that the aging process may be accelerated in schizophrenia. However …

Objective: Patients with first-episode psychosis have a high prevalence of tobacco use. We
aimed to examine the prevalence and course of tobacco use during early psychosis using …

Stress and stress-induced glucocorticoids have been implicated in many neuropsychiatric
disorders including schizophrenia. In addition, the neurotrophin, brain derived neurotrophic …

Increasing evidence suggests that epigenetic factors have critical roles in gene regulation in
neuropsychiatric disorders and in aging, both of which are typically associated with a wide …