Ischemia and reperfusion—from mechanism to translation
Ischemia and reperfusion–elicited tissue injury contributes to morbidity and mortality in a
wide range of pathologies, including myocardial infarction, ischemic stroke, acute kidney …
wide range of pathologies, including myocardial infarction, ischemic stroke, acute kidney …
Humanized mice for immune system investigation: progress, promise and challenges
LD Shultz, MA Brehm, JV Garcia-Martinez… - Nature Reviews …, 2012 - nature.com
Significant advances in our understanding of the in vivo functions of human cells and tissues
and the human immune system have resulted from the development of'humanized'mouse …
and the human immune system have resulted from the development of'humanized'mouse …
Mechanisms of mesenchymal stromal cell immunomodulation
K English - Immunology and cell biology, 2013 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …
Regulatory immune cells in transplantation
KJ Wood, A Bushell, J Hester - Nature Reviews Immunology, 2012 - nature.com
Immune regulation is fundamental to any immune response to ensure that it is appropriate
for the perceived threat to the host. Following cell and organ transplantation, it is essential to …
for the perceived threat to the host. Following cell and organ transplantation, it is essential to …
Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells
P Sagoo, N Ali, G Garg, FO Nestle, RI Lechler… - Science translational …, 2011 - science.org
Graft rejection by the immune system is a major cause of transplant failure. Lifelong
immunosuppression decreases the incidence of graft rejection; however, nonspecific …
immunosuppression decreases the incidence of graft rejection; however, nonspecific …
Feasibility, long‐term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients
Short‐term outcomes in kidney transplantation are marred by progressive transplant failure
and mortality secondary to immunosuppression toxicity. Immune modulation with autologous …
and mortality secondary to immunosuppression toxicity. Immune modulation with autologous …
Immunological considerations and challenges for regenerative cellular therapies
The central goal of regenerative medicine is to replace damaged or diseased tissue with
cells that integrate and function optimally. The capacity of pluripotent stem cells to produce …
cells that integrate and function optimally. The capacity of pluripotent stem cells to produce …
Mesenchymal stromal cells: facilitators of successful transplantation?
Mesenchymal stromal/stem cells (MSCs) possess immunomodulatory and reparative
properties. Through specific interactions with immune cells that participate in both innate …
properties. Through specific interactions with immune cells that participate in both innate …
[HTML][HTML] Bioactive peptides from fisheries residues: A review of use of papain in proteolysis reactions
Papain is a cysteine endopeptidase of vegetal origin (papaya (Carica papaya L.) with
diverse applications in food technology. In this review we have focused our attention on its …
diverse applications in food technology. In this review we have focused our attention on its …
Suppression of murine colitis and its associated cancer by carcinoembryonic antigen-specific regulatory T cells
D Blat, E Zigmond, Z Alteber, T Waks, Z Eshhar - Molecular Therapy, 2014 - cell.com
The adoptive transfer of regulatory T cells (Tregs) offers a promising strategy to combat
pathologies that are characterized by aberrant immune activation, including graft rejection …
pathologies that are characterized by aberrant immune activation, including graft rejection …