Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Epigenetic remodeling is a molecular hallmark of gliomas, and it has been identified as a
key mediator of glioma progression. Epigenetic dysregulation contributes to gliomagenesis …

Tumor-derived exosomes (TDEs) play pivotal roles in several aspects of cancer biology. It is
now evident that TDEs also favor tumor growth by negatively affecting anti-tumor immunity …

Exosome, a subpopulation of extracellular vesicles, plays diverse roles in various biological
processes. As one of the most abundant components of exosomes, exosomal proteins have …

Background Solid tumors such as glioblastoma (GBM) exhibit hypoxic zones that are
associated with poor prognosis and immunosuppression through multiple cell intrinsic …

Primary tumors secrete a variety of factors to turn distant microenvironments into favorable
and fertile 'soil'for subsequent metastases. Among these 'seeding'factors that initiate pre …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Extracellular vesicles (EVs) play a key role in health and disease, including cancer. Tumors
produce a mix of EVs differing in size, cellular origin, biogenesis and molecular content …

Exosomes, small yet vital extracellular vesicles, play an integral role in intercellular
communication. They transport critical components, such as proteins, lipid bilayers, DNA …

Glioblastoma is the most aggressive variant of glioma, the tumor of glial origin which
accounts for 80% of brain tumors. Glioblastoma is characterized by astoundingly poor …