Malaria is a serious public health problem that affects mostly the poorest countries in the
world, killing more than 400,000 people per year, mainly children under 5 years old. Among …

Malaria continues to be one of the most devastating diseases impacting global health.
Although there have been significant reductions in global malaria incidence and mortality …

Asymptomatic carriers of Plasmodium parasites hamper malaria control and eradication.
Achieving malaria eradication requires ultrasensitive diagnostics for low parasite density …

Over the past two decades efforts to control malaria have halved the number of cases
globally, yet burdens remain high in much of Africa and the elimination of malaria has not …

Background Nucleic acid amplification is the most sensitive and specific method to detect
Plasmodium falciparum. However the polymerase chain reaction remains laboratory-based …

Background Planning and evaluating malaria control strategies relies on accurate definition
of parasite prevalence in the population. A large proportion of asymptomatic parasite …

There is a critical need for develo** new malaria diagnostic tools that are sensitive, cost
effective and capable of performing large scale diagnosis. The real-time PCR methods are …

Haemosporida is a diverse group of vector-borne parasitic protozoa, ubiquitous in terrestrial
vertebrates worldwide. The renewed interest in their diversity has been driven by the …

Abstract Background Nested PCRs based on the Plasmodium 18s-rRNA gene have been
extensively used for human malaria diagnosis. However, they are not practical when large …

A distinctive feature of Plasmodium vivax infections is the overall low parasite density in
peripheral blood. Thus, identifying asymptomatic infected individuals in endemic …