The development of the mammalian cerebellum is orchestrated by both cell-autonomous
programs and inductive environmental influences. Here, we describe the main processes of …

Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the
brain: at least 99% of all cerebellar neurons are granule cells. In this review article, we first …

While a massive and progressive neuronal loss in specific areas such as the hippocampus
and cortex unequivocally underlies cognitive deterioration and memory loss in Alzheimer's …

Signaling by the transforming growth factor β (TGF-β) family is necessary for proper neural
development and function throughout life. Sequential waves of activation, inhibition, and …

In the last 20 years, it has become clear that developmental genes and their regulators,
noncoding RNAs including microRNAs and long-noncoding RNAs, within signaling …

The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

The glial cells of the cerebellum, and particularly astrocytes and oligodendrocytes, are
characterized by a remarkable phenotypic variety, in which highly peculiar morphological …

Medulloblastoma (MB) is the most common malignant pediatric brain tumor and is thought to
arise from genetic anomalies in developmental pathways required for the normal maturation …

The cerebellum has a well-established role in controlling motor functions such coordination,
balance, posture, and skilled learning. There is mounting evidence that it might also play a …

Background Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly
conserved serine/threonine protein kinase encoded by two genes that generate two related …