First discovered by Friedenstein in 1976, mesenchymal stem cells (MSCs) are adult stem
cells found throughout the body that share a fixed set of characteristics. Discovered initially …

Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …

Transplantation of synovial fluid-derived mesenchymal stem cells (SF-MSCs) is a viable
therapy for cartilage degeneration of osteoarthritis (OA). But controlling chondrogenic …

Exosomes participate in many physiological and pathological processes by regulating cell–
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …

Background Osteoarthritis (OA) is the most common joint disease worldwide. In the past
decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA. A …

Cartilage is frequently damaged with a limited capacity for repair. Current treatment
strategies are insufficient as they form fibrocartilage as opposed to hyaline cartilage, and do …

Osteoarthritis results in irreparable loss of articular cartilage. Due to its avascular nature and
low mitotic activity, cartilage has little intrinsic capacity for repair. Cartilage loss leads to pain …

Magnesium deficiency increases the generation of pro-inflammatory cytokines, which is
consistently accompanied by the sensitization of cells such as neutrophils, macrophages …

The prevalence of osteoarthritis (OA), a degenerative disorder of joints, has substantially
increased in recent years. Its key pathogenic hallmarks include articular cartilage …

In the recent times, stem cell biology has garnered the attention of the scientific fraternity and
the general public alike due to the immense therapeutic potential that it holds in the field of …