MicroRNAs as potential biomarkers in atherosclerosis
A Churov, V Summerhill, A Grechko… - International Journal of …, 2019 - mdpi.com
Atherosclerosis is a complex multifactorial disease that, despite advances in lifestyle
management and drug therapy, remains to be the major cause of high morbidity and …
management and drug therapy, remains to be the major cause of high morbidity and …
Non-coding RNAs in regulating plaque progression and remodeling of extracellular matrix in atherosclerosis
Non-coding RNAs (ncRNAs) regulate cell proliferation, migration, differentiation,
inflammation, metabolism of clinically important biomolecules, and other cellular processes …
inflammation, metabolism of clinically important biomolecules, and other cellular processes …
Micro RNA expression in circulating microvesicles predicts cardiovascular events in patients with coronary artery disease
F Jansen, X Yang, S Proebsting… - Journal of the …, 2014 - Am Heart Assoc
Background Circulating micro RNA s (mi RNA s) are differentially regulated and selectively
packaged in microvesicles (MVs). We evaluated whether circulating vascular and …
packaged in microvesicles (MVs). We evaluated whether circulating vascular and …
miR-128-3p is a novel regulator of vascular smooth muscle cell phenotypic switch and vascular diseases
Rationale: MicroRNAs (miRNAs, miRs) are small noncoding RNAs that modulate gene
expression by negatively regulating translation of target genes. Although the role of several …
expression by negatively regulating translation of target genes. Although the role of several …
Atherosclerotic conditions promote the packaging of functional microRNA-92a-3p into endothelial microvesicles
Rationale: Microvesicle-incorporated microRNAs (miRs) are biomarkers and effectors of
cardiovascular disease. Whether microvesicle-miR expression is regulated in coronary …
cardiovascular disease. Whether microvesicle-miR expression is regulated in coronary …
SOX2–LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors
F Cimadamore, A Amador-Arjona… - Proceedings of the …, 2013 - National Acad Sciences
The transcription factor SRY (sex-determining region)-box 2 (SOX2) is an important
functional marker of neural precursor cells (NPCs) and plays a critical role in self-renewal …
functional marker of neural precursor cells (NPCs) and plays a critical role in self-renewal …
Myotube-derived exosomal miRNAs downregulate Sirtuin1 in myoblasts during muscle cell differentiation
A Forterre, A Jalabert, K Chikh, S Pesenti, V Euthine… - Cell cycle, 2014 - Taylor & Francis
It has recently been established that exosomes can mediate intercellular cross-talk under
normal and pathological conditions through the transfer of specific miRNAs. As muscle cells …
normal and pathological conditions through the transfer of specific miRNAs. As muscle cells …
Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer
CJ Chang, CC Hsu, CH Chang, LL Tsai… - Oncology …, 2011 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide. Let-7 family has
been shown to function as a tumor suppressor through regulating multiple oncogenic …
been shown to function as a tumor suppressor through regulating multiple oncogenic …
Investigating underlying molecular mechanisms, signaling pathways, emerging therapeutic approaches in pancreatic cancer
Pancreatic adenocarcinoma, a clinically challenging malignancy constitutes a significant
contributor to cancer-related mortality, characterized by an inherently poor prognosis. This …
contributor to cancer-related mortality, characterized by an inherently poor prognosis. This …
Decoding microRNA drivers in atherosclerosis
An estimated 97% of the human genome consists of non-protein-coding sequences. As our
understanding of genome regulation improves, this has led to the characterization of a …
understanding of genome regulation improves, this has led to the characterization of a …