Individual proteins and protein complexes undergo various motion types, including free
diffusion, confinement, subdiffusion and directed motion. Different motion behaviours reflect …

Bacteria are continuously exposed to numerous endogenous and exogenous DNA-
damaging agents. To maintain genome integrity and ensure cell survival, bacteria have …

Liquid-liquid phase-separated (LLPS) states are key to compartmentalizing components in
the absence of membranes; however, it is unclear whether LLPS condensates are actively …

The bacterial SOS response represents a paradigm of gene networks controlled by a master
transcriptional regulator. Self-cleavage of the SOS repressor LexA induces a wide range of …

In the past decades, advances in microscopy have made it possible to study the dynamics of
individual biomolecules in vitro and resolve intramolecular kinetics that would otherwise be …

Despite their diverse biochemical characteristics and functions, all DNA-binding proteins
share the ability to accurately locate their target sites among the vast excess of non-target …

Acid-resistant bacteria are more and more widely used in industrial production due to their
unique acid-resistant properties. In order to survive in various acidic environments, acid …

Understanding the interplay between phenotypic and genetic adaptation is a focus of
evolutionary biology. In bacteria, the oxidative stress response prevents mutagenesis by …

Protein diffusion is crucial for understanding the formation of protein complexes in vivo and
has been the subject of many fluorescence microscopy studies in cells; however, such …

Transcription-coupled DNA repair (TCR) acts on lesions in the transcribed strand of active
genes. Helix distorting adducts and other forms of DNA damage often interfere with the …