[HTML][HTML] Organ-on-a-chip: a survey of technical results and problems

AE Danku, EH Dulf, C Braicu, A Jurj… - … in bioengineering and …, 2022 - frontiersin.org
Organ-on-a-chip (OoC), also known as micro physiological systems or 'tissue chips' have
attracted substantial interest in recent years due to their numerous applications, especially in …

[HTML][HTML] Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

U Marx, TB Andersson, A Bahinski, M Beilmann… - Altex, 2016 - ncbi.nlm.nih.gov
The recent advent of microphysiological systems–microfluidic biomimetic devices that aspire
to emulate the biology of human tissues, organs and circulation in vitro–is envisaged to …

[HTML][HTML] Microfluidic platforms for cell cultures and investigations

ML Coluccio, G Perozziello, N Malara, E Parrotta… - Microelectronic …, 2019 - Elsevier
This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …

Skin-on-a-chip models: General overview and future perspectives

I Risueño, L Valencia, JL Jorcano, D Velasco - APL bioengineering, 2021 - pubs.aip.org
Over the last few years, several advances have been made toward the development and
production of in vitro human skin models for the analysis and testing of cosmetic and …

Integrating biosensors in organs-on-chip devices: A perspective on current strategies to monitor microphysiological systems

E Ferrari, C Palma, S Vesentini, P Occhetta, M Rasponi - Biosensors, 2020 - mdpi.com
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced
in vitro tools able to replicate essential functions of human organs. Owing to their …

3D bioprinting for high-throughput screening: Drug screening, disease modeling, and precision medicine applications

A Mazzocchi, S Soker, A Skardal - Applied Physics Reviews, 2019 - pubs.aip.org
High-throughput technologies have become essential in many fields of pharmaceutical and
biological development and production. Such technologies were initially developed with …

New generation of bioreactors that advance extracellular matrix modelling and tissue engineering

S Ahmed, VM Chauhan, AM Ghaemmaghami… - Biotechnology …, 2019 - Springer
Bioreactors hold a lot of promise for tissue engineering and regenerative medicine
applications. They have multiple uses including cell cultivation for therapeutic production …

Investigating nonalcoholic fatty liver disease in a liver-on-a-chip microfluidic device

M Gori, MC Simonelli, SM Giannitelli, L Businaro… - PloS one, 2016 - journals.plos.org
Background and Aim Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease
worldwide, ranging from simple steatosis to nonalcoholic steatohepatitis, which may …

Organ-on-a-chip engineering: Toward bridging the gap between lab and industry

Q Ramadan, M Zourob - Biomicrofluidics, 2020 - pubs.aip.org
Organ-on-a-chip (OOC) is a very ambitious emerging technology with a high potential to
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …

Multi-organs-on-chips: towards long-term biomedical investigations

Y Zhao, RK Kankala, SB Wang, AZ Chen - Molecules, 2019 - mdpi.com
With advantageous features such as minimizing the cost, time, and sample size
requirements, organ-on-a-chip (OOC) systems have garnered enormous interest from …