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The triumphs and limitations of computational methods for scRNA-seq
PV Kharchenko - Nature methods, 2021 - nature.com
The rapid progress of protocols for sequencing single-cell transcriptomes over the past
decade has been accompanied by equally impressive advances in the computational …
decade has been accompanied by equally impressive advances in the computational …
Regulation of immune responses by the airway epithelial cell landscape
The community of cells lining our airways plays a collaborative role in the preservation of
immune homeostasis in the lung and provides protection from the pathogens and pollutants …
immune homeostasis in the lung and provides protection from the pathogens and pollutants …
CellRank 2: unified fate map** in multiview single-cell data
Single-cell RNA sequencing allows us to model cellular state dynamics and fate decisions
using expression similarity or RNA velocity to reconstruct state-change trajectories; however …
using expression similarity or RNA velocity to reconstruct state-change trajectories; however …
Dictionary learning for integrative, multimodal and scalable single-cell analysis
Map** single-cell sequencing profiles to comprehensive reference datasets provides a
powerful alternative to unsupervised analysis. However, most reference datasets are …
powerful alternative to unsupervised analysis. However, most reference datasets are …
Pan-cancer single-cell landscape of tumor-infiltrating T cells
Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development
During development, animals generate distinct cell populations with specific identities,
functions, and morphologies. We mapped transcriptionally distinct populations across …
functions, and morphologies. We mapped transcriptionally distinct populations across …
A new genomic framework to categorize pediatric acute myeloid leukemia
Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific
driver alterations, many of which are underrepresented in the current classification schemas …
driver alterations, many of which are underrepresented in the current classification schemas …