Genome editing in the treatment of ocular diseases

EH Choi, S Suh, AE Sears, R Hołubowicz… - … & molecular medicine, 2023 - nature.com
Genome-editing technologies have ushered in a new era in gene therapy, providing novel
therapeutic strategies for a wide range of diseases, including both genetic and nongenetic …

Stem cell therapy for inherited retinal diseases: a systematic review and meta-analysis

X Chen, N Xu, J Li, M Zhao, L Huang - Stem Cell Research & Therapy, 2023 - Springer
Purpose Stem cell therapy is a promising therapeutic approach for inherited retinal diseases
(IRDs). This study aims to quantitatively examine the effectiveness and safety of stem cell …

DNA-Based Nonviral Gene Therapy─ Challenging but Promising

X Guan, Y Pei, J Song - Molecular Pharmaceutics, 2024 - ACS Publications
Over the past decades, significant progress has been made in utilizing nucleic acids,
including DNA and RNA molecules, for therapeutic purposes. For DNA molecules, although …

An update on visual prosthesis

KA Ramirez, LE Drew-Bear, M Vega-Garces… - International Journal of …, 2023 - Springer
Purpose To review the available evidence on the different retinal and visual prostheses for
patients with retinitis pigmentosa and new implants for other indications including dry age …

New Perspectives in Stem Cell Transplantation and Associated Therapies to Treat Retinal Diseases: From Gene Editing to 3D Bioprinting

G Bovi dos Santos, TH de Lima-Vasconcellos… - Stem Cell Reviews and …, 2024 - Springer
Inherited and non-inherited retinopathies can affect distinct cell types, leading to progressive
cell death and visual loss. In the last years, new approaches have indicated exciting …

A review of pharmacological mechanisms, challenges and prospects of macromolecular glycopeptides

Y Gao, X Chen, J Duan, P **ao - International Journal of Biological …, 2025 - Elsevier
Macromolecular glycopeptides are natural products derived from various sources,
distinguished by their structural diversity, multifaceted biological activities, and low toxicity …

[HTML][HTML] Retinitis Pigmentosa and Therapeutic Approaches: A Systematic Review

F Confalonieri, A La Rosa, G Ottonelli… - Journal of Clinical …, 2024 - mdpi.com
Background: Retinitis pigmentosa (RP) is a group of hereditary retinal dystrophies
characterized by progressive degeneration of photoreceptor cells, which results in …

[HTML][HTML] Overview of Retinal Prosthesis and Future Directions

JY Moon, RN Sather III, SR Montezuma - retinalphysician.com
Retinal prosthesis devices, also known as bionic eyes, are implantable electronic devices
designed to convert light into electrical signals and transmit them to retinal tissue, the optic …

¿ La aplicación de Células Madre en enfermos de Retinitis Pigmentosa podría emplearse como nueva estrategia terapéutica? Revisión Sistemática

Á Ríos Tolbaños - 2023 - uvadoc.uva.es
La Retinitis Pigmentosa engloba un conjunto de distrofias de la retina, caracterizadas por
una disminución de la visión, presenta un componente hereditario y suele manifestarse en …