Molecular dynamics (MD) simulations have become increasingly useful in the modern drug
development process. In this review, we give a broad overview of the current application …

Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

In this work, an important step is taken towards the bioavailability improvement of poorly
water-soluble drugs, such as flubendazole (Flu), posing a challenge in the current …

Accurately predicting new polymers' properties with machine learning models apriori to
synthesis has potential to significantly accelerate new polymers' discovery and …

We used dielectric spectroscopy to access the molecular dynamics of three isomers with a
structure based on a sizable, partially rigid, and non-polar core connected to a polar …

Amorphous solid dispersions (ASD) are known to enhance the absorption of poorly water-
soluble drugs. In this work we synthesise well-defined Polyvinylpyrrolidone (PVP) to …

Amorphous solid dispersions of pharmaceuticals often show improved solubility over
crystalline forms. However, the crystallization of amorphous solid dispersions during …

In this paper, we propose one-step synthetic strategies for obtaining well-defined linear and
star-shaped polyvinylpyrrolidone (lin PVP and star PVP). The produced macromolecules …

The aims of this systematic review are to explore the possibilities of using the positron
annihilation lifetime spectroscopy (PALS) method in the pharmaceutical industry and to …

The present study evaluated the specific intermolecular interactions between
carbamazepine (CBZ) and substituents of hypromellose acetate succinate (HPMC-AS), as …