Sleep and circadian rhythm disruption are frequently observed in patients with psychiatric
disorders and neurodegenerative disease. The abnormal sleep that is experienced by these …

Ageing leads to a functional deterioration of many brain systems, including the circadian
clock—an internal time-kee** system that generates∼ 24-hour rhythms in physiology and …

The circadian system is an intricate molecular network of coordinating circadian clocks that
organize the internal synchrony of the organism in response to the environment. These …

This article discusses the role that melatonin may have in the prevention and treatment of
Parkinson's disease (PD). In parkinsonian patients circulating melatonin levels are …

The circadian system regulates biological rhythmicity in the human body. The role of the
circadian system in neurological disorders is a theme that is attracting an increasing amount …

Parkinson's disease (PD) is the second most common neurodegenerative disorder that
affects over one million individuals in the US alone. PD is characterized by a plethora of …

The blood–brain barrier (BBB) impairment plays a crucial role in the pathological processes
of aging-accompanied neurological diseases (AAND). Meanwhile, circadian rhythms …

In the last decade, there was the seminal discovery of melanopsin-expressing retinal
ganglion cells (mRGCs) as a new class of photoreceptors that subserve the …

Circadian disruption is being increasingly recognized as a critical factor in the development
and progression of Parkinson's disease (PD). This review aims to provide an in-depth …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders, but it is
often diagnosed after the majority of dopaminergic cells are already damaged. It is critical to …