Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

[HTML][HTML] Exosome-mediated immunosuppression in tumor microenvironments

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X Su, X Liu, Y **e, M Chen, C Zheng, H Zhong, M Li - ACS nano, 2023 - ACS Publications
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …

Facilitating in situ tumor imaging with a tetrahedral DNA framework‐enhanced hybridization chain reaction probe

B Zhang, T Tian, D **ao, S Gao… - Advanced Functional …, 2022 - Wiley Online Library
Rapid and efficient tools for early cancer detection have diagnostic and therapeutic value.
Given that the DNA hairpin‐based hybridization chain reaction (HCR) is effective in …

Advances in surface plasmon resonance–based biosensor technologies for cancer biomarker detection

A Azzouz, L Hejji, KH Kim, D Kukkar, B Souhail… - Biosensors and …, 2022 - Elsevier
Surface plasmon resonance approach is a highly useful option to offer optical and label-free
detection of target bioanalytes with numerous advantages (eg, low-cost fabrication …

Simultaneous detection of tumor derived exosomal protein–MicroRNA pairs with an exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

Exploring the versatility of exosomes: a review on isolation, characterization, detection methods, and diverse applications

O Altıntaş, Y Saylan - Analytical chemistry, 2023 - ACS Publications
Extracellular vesicles (EVs) are crucial mediators of intercellular communication and can be
classified based on their physical properties, biomolecular structure, and origin. Among EVs …

Optical, electrochemical and electrical (nano) biosensors for detection of exosomes: A comprehensive overview

L Xu, N Shoaie, F Jahanpeyma, J Zhao… - Biosensors and …, 2020 - Elsevier
Exosomes are small extracellular vesicles involved in many physiological activities of cells
in the human body. Exosomes from cancer cells have great potential to be applied in clinical …

[HTML][HTML] Biosensors as diagnostic tools in clinical applications

C Lino, S Barrias, R Chaves, F Adega… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Nowadays, the development of new technological solutions in the medical field, in particular
biosensors, is a priority and a ground for great scientific and financial investment. From …

Advanced mass spectrometric and spectroscopic methods coupled with machine learning for in vitro diagnosis

X Chen, W Shu, L Zhao, J Wan - View, 2023 - Wiley Online Library
In vitro diagnosis (IVD) is one vital component of medical tests that detects biological
samples of tissues or bio‐fluids. Recently, mass spectrometry and spectroscopy have been …