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Metformin: update on mechanisms of action and repurposing potential
Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …
[HTML][HTML] Atherosclerosis: recent developments
JLM Björkegren, AJ Lusis - Cell, 2022 - cell.com
Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …
RNA modifications: importance in immune cell biology and related diseases
L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …
including generation, transportation, function, and metabolization, they act as critical …
Inflammation and atherosclerosis: signaling pathways and therapeutic intervention
P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
Atherosclerosis: Known and unknown
J Fan, T Watanabe - Pathology international, 2022 - Wiley Online Library
Atherosclerotic disease, such as myocardial infarction and stroke, is the number one killer
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …
Atherosclerosis and inflammation: Insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
Gut Parabacteroides merdae protects against cardiovascular damage by enhancing branched-chain amino acid catabolism
Obesity, dyslipidemia and gut dysbiosis are all linked to cardiovascular diseases. A
Ganoderma meroterpene derivative (GMD) has been shown to alleviate obesity and …
Ganoderma meroterpene derivative (GMD) has been shown to alleviate obesity and …
Modulating Plaque Inflammation via Targeted mRNA Nanoparticles for the Treatment of Atherosclerosis
Atherosclerosis is a common pathology present in many cardiovascular diseases. Although
the current therapies (including statins and inhibitors of the serine protease PCSK9) can …
the current therapies (including statins and inhibitors of the serine protease PCSK9) can …
A bibliometric analysis of T cell and atherosclerosis
N Wei, Y Xu, Y Li, J Shi, X Zhang, Y You… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis (AS) is widespread and develops into circulatory system problems. T cells
play an essential regulatory role in AS occurrence and development. So far, there is no …
play an essential regulatory role in AS occurrence and development. So far, there is no …