GLP-1 programs the neurovascular landscape

B Chen, X Yu, C Horvath-Diano, MJ Ortuño… - Cell Metabolism, 2024 - cell.com
Readily available nutrient-rich foods exploit our inherent drive to overconsume, creating an
environment of overnutrition. This transformative setting has led to persistent health issues …

Harnessing myelin water fraction as an imaging biomarker of human cerebral aging, neurodegenerative diseases, and risk factors influencing myelination: A review

ME Faulkner, Z Gong, A Guo, JP Laporte… - Journal of …, 2024 - Wiley Online Library
Myelin water fraction (MWF) imaging has emerged as a promising magnetic resonance
imaging (MRI) biomarker for investigating brain function and composition. This …

[HTML][HTML] The diamagnetic component map from quantitative susceptibility map** (QSM) source separation reveals pathological alteration in Alzheimer's disease …

M Ahmed, J Chen, A Arani, ML Senjem, PM Cogswell… - Neuroimage, 2023 - Elsevier
A sensitive and accurate imaging technique capable of tracking the disease progression of
Alzheimer's Disease (AD) driven amnestic dementia would be beneficial. A currently …

C-NODDI: a constrained NODDI model for axonal density and orientation determinations in cerebral white matter

MH Alsameen, Z Gong, W Qian, M Kiely… - Frontiers in …, 2023 - frontiersin.org
Purpose Neurite orientation dispersion and density imaging (NODDI) provides measures of
neurite density and dispersion through computation of the neurite density index (NDI) and …

Cognitive, behavioral, neuroimaging and inflammatory biomarkers after hospitalization for COVID-19 in Brazil

FK Sudo, TP Pinto, FGQ Barros-Aragão… - Brain, Behavior, and …, 2024 - Elsevier
Abstract Post-COVID-19 Condition (PCC) refers to a multisystemic syndrome that persists for
months after SARS-CoV-2 infection. Cognitive deficits, fatigue, depression, and anxiety are …

The effect of the human brainstem myelination on gait speed in normative aging

MABS Akhonda, ME Faulkner, Z Gong… - The Journals of …, 2023 - academic.oup.com
The brainstem functions as a relay and integrative brain center and plays an essential role in
motor function. Whether brainstem tissue deterioration, including demyelination, affects …

Cortical amyloid-beta burden is associated with changes in intracortical myelin in cognitively normal older adults

M Fernandez-Alvarez, M Atienza, JL Cantero - Translational Psychiatry, 2023 - nature.com
Amyloid-beta (Aβ) aggregates and myelin breakdown are among the earliest detrimental
effects of Alzheimer's disease (AD), likely inducing abnormal patterns of neuronal …

Central myelin dysfunction bridges obesity and neurological diseases

B Chen, E de Launoit, N Renier… - Trends in Endocrinology & …, 2024 - cell.com
The central nervous system (CNS) relies on myelin for proper functioning. Myelin
remodeling is a risk factor for neurometabolic and endocrine malfunction, resulting in …

Intracortical myelin across laminae in adult individuals with 47, XXX: a 7 Tesla MRI study

C Serrarens, J Ruiz-Fernandez, M Otter… - Cerebral …, 2024 - academic.oup.com
Abstract 47, XXX (Triple X syndrome) is a sex chromosome aneuploidy characterized by the
presence of a supernumerary X chromosome in affected females and is associated with a …

[HTML][HTML] Chemotherapy-induced cognitive impairment and glia: A new take on chemobrain?

M Barbosa-Azevedo, A Dias-Carvalho… - Toxicology and Applied …, 2024 - Elsevier
The significant rise in cancer survivorship stands out as one of the most notable
achievements of modern science. However, this comes with a significant burden, as cancer …