[HTML][HTML] Epigenetic Mechanisms Underlying Sex Differences in Neurodegenerative Diseases

A Stoccoro - Biology, 2025 - mdpi.com
Neurodegenerative diseases are characterized by profound differences between females
and males in terms of incidence, clinical presentation, and disease progression …

Single-nucleus multiomic atlas of frontal cortex in amyotrophic lateral sclerosis with a deep learning-based decoding of alternative polyadenylation mechanisms

PM McKeever, AM Sababi, R Sharma, N Khuu, Z Xu… - bioRxiv, 2023 - biorxiv.org
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are two
age-related and fatal neurodegenerative disorders that lie on a shared disease spectrum …

[HTML][HTML] Transcriptomic profiling of symptomatic and end-stage SOD1-G93A transgenic mice reveals extracellular matrix components as key players in ALS …

S Rossi, M Milani, I Della Valle, S Apolloni - Biochimica et Biophysica Acta …, 2025 - Elsevier
ALS is a neurodegenerative disease marked by the loss of motor neurons.• Damaged
neurons are not regenerated but attract immune cells, fibroblasts, and astrocytes.• Research …

A dataset profiling the multiomic landscape of the prefrontal cortex in amyotrophic lateral sclerosis

F Hausmann, L Caldi Gomes, S Hänzelmann… - …, 2024 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease, which still
lacks effective disease-modifying therapies. Similar to other neurodegenerative disorders …

[PDF][PDF] Differentially expressed lncRNAs in SOD1G93A mice skeletal muscle: H19, Myhas and Neat1 as potential biomarkers in amyotrophic lateral sclerosis

R Osta - 2024 - zaguan.unizar.es
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized
by progressive motor function and muscle mass loss. Despite extensive research in the field …

Investigating ALS genetic epidemiology complexity through a multi-analytical approach and introducing GenUInE, a tool for genomic signals prioritization

A Brusati - 2025 - tesidottorato.depositolegale.it
Abstract Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disease
characterized by motor neuron degeneration in both familial (fALS) and sporadic (sALS) …

Differentially expressed lncRNAs in SOD1G93A mice skeletal muscle: H19, Myhas and Neat1 as potential biomarkers in amyotrophic later

T López-Royo, A García-Redondo, R Osta… - 2024 - zaguan.unizar.es
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized
by progressive motor function and muscle mass loss. Despite extensive research in the field …

Differentially expressed lncRNAs in SOD1G93A mice skeletal muscle: H19, Myhas and Neat1 as potential biomarkers in amyotrophic lateral sclerosis

T López-Royo, L Moreno-Martínez… - Open …, 2024 - royalsocietypublishing.org
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized
by progressive motor function and muscle mass loss. Despite extensive research in the field …