Considerations for the development of cost‐effective cell culture media for cultivated meat production

EN O'Neill, ZA Cosenza, K Baar… - … Reviews in Food …, 2021 - Wiley Online Library
Innovation in cultivated meat development has been rapidly accelerating in recent years
because it holds the potential to help attenuate issues facing production of dietary protein for …

Oxygen toxicity: cellular mechanisms in normobaric hyperoxia

R Alva, M Mirza, A Baiton, L Lazuran… - Cell Biology and …, 2023 - Springer
In clinical settings, oxygen therapy is administered to preterm neonates and to adults with
acute and chronic conditions such as COVID-19, pulmonary fibrosis, sepsis, cardiac arrest …

Dietary fructose improves intestinal cell survival and nutrient absorption

SR Taylor, S Ramsamooj, RJ Liang, A Katti… - Nature, 2021 - nature.com
Fructose consumption is linked to the rising incidence of obesity and cancer, which are two
of the leading causes of morbidity and mortality globally,. Dietary fructose metabolism …

[PDF][PDF] Guidance document on good cell and tissue culture practice 2.0 (GCCP 2.0)

D Pamies, M Leist, S Coecke, G Bowe, D Allen… - 2022 - repository.ubn.ru.nl
Abstract Good Cell and Tissue Culture Practice (GCCP) 2.0 is an updated guidance
document from GCCP 1.0 (published by ECVAM in 2005), which was developed for practical …

In Vitro Research Reproducibility: Kee** Up High Standards

C Hirsch, S Schildknecht - Frontiers in pharmacology, 2019 - frontiersin.org
Concern regarding the reproducibility of observations in life science research has emerged
in recent years, particularly in view of unfavorable experiences with preclinical in vivo …

Scaffold-based 3D cell culture models in cancer research

WH Abuwatfa, WG Pitt, GA Husseini - Journal of Biomedical Science, 2024 - Springer
Abstract Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer
research, offering significant advantages over traditional two-dimensional (2D) cell culture …

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding

M Barroso, MG Monaghan, R Niesner… - Advanced Drug Delivery …, 2023 - Elsevier
Organoid models have been used to address important questions in developmental and
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …

Oxygen control: the often overlooked but essential piece to create better in vitro systems

V Palacio-Castañeda, N Velthuijs, S Le Gac… - Lab on a Chip, 2022 - pubs.rsc.org
Variations in oxygen levels play key roles in numerous physiological and pathological
processes, but are often not properly controlled in in vitro models, introducing a significant …

Supraphysiological oxygen levels in mammalian cell culture: current state and future perspectives

R Alva, GL Gardner, P Liang, JA Stuart - Cells, 2022 - mdpi.com
Most conventional incubators used in cell culture do not regulate O2 levels, making the
headspace O2 concentration~ 18%. In contrast, most human tissues are exposed to 2–6 …

Polylactic is a sustainable, low absorption, low autofluorescence alternative to other plastics for microfluidic and organ-on-chip applications

AE Ongaro, D Di Giuseppe, A Kermanizadeh… - Analytical …, 2020 - ACS Publications
Organ-on-chip (OOC) devices are miniaturized devices replacing animal models in drug
discovery and toxicology studies. The majority of OOC devices are made from …