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[HTML][HTML] Sea anemone toxins: A structural overview
Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different
molecular scaffolds reported to date. These venom components have traditionally been …
molecular scaffolds reported to date. These venom components have traditionally been …
Strategies for heterologous expression, synthesis, and purification of animal venom toxins
Animal venoms are complex mixtures containing peptides and proteins known as toxins,
which are responsible for the deleterious effect of envenomations. Across the animal …
which are responsible for the deleterious effect of envenomations. Across the animal …
[HTML][HTML] Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux
Pore-forming toxins (PFTs) form holes in membranes causing one of the most catastrophic
damages to a target cell. Target organisms have evolved a regulated response against PFTs …
damages to a target cell. Target organisms have evolved a regulated response against PFTs …
Pore-forming toxins in Cnidaria
M Podobnik, G Anderluh - Seminars in Cell & Developmental Biology, 2017 - Elsevier
The ancient phylum of Cnidaria contains many aquatic species with peculiar lifestyle. In
order to survive, these organisms have evolved attack and defense mechanisms that are …
order to survive, these organisms have evolved attack and defense mechanisms that are …
[HTML][HTML] Magnificamide, a β-Defensin-Like Peptide from the Mucus of the Sea Anemone Heteractis magnifica, Is a Strong Inhibitor of Mammalian α-Amylases
O Sintsova, I Gladkikh, A Kalinovskii, E Zelepuga… - Marine Drugs, 2019 - mdpi.com
Sea anemones' venom is rich in peptides acting on different biological targets, mainly on
cytoplasmic membranes and ion channels. These animals are also a source of pancreatic α …
cytoplasmic membranes and ion channels. These animals are also a source of pancreatic α …
The sea anemone neurotoxins modulating sodium channels: an insight at structure and functional activity after four decades of investigation
MM Monastyrnaya, RS Kalina, EP Kozlovskaya - Toxins, 2022 - mdpi.com
Many human cardiovascular and neurological disorders (such as ischemia, epileptic
seizures, traumatic brain injury, neuropathic pain, etc.) are associated with the abnormal …
seizures, traumatic brain injury, neuropathic pain, etc.) are associated with the abnormal …
[HTML][HTML] Evolution of the cytolytic pore-forming proteins (Actinoporins) in sea anemones
Sea anemones (Cnidaria, Anthozoa, and Actiniaria) use toxic peptides to incapacitate and
immobilize prey and to deter potential predators. Their toxin arsenal is complex, targeting a …
immobilize prey and to deter potential predators. Their toxin arsenal is complex, targeting a …
[HTML][HTML] The chemical armament of reef-building corals: inter-and intra-specific variation and the identification of an unusual actinoporin in Stylophora pistilata
H Ben-Ari, M Paz, D Sher - Scientific reports, 2018 - nature.com
Corals, like other cnidarians, are venomous animals that rely on stinging cells (nematocytes)
and their toxins to catch prey and defend themselves against predators. However, little is …
and their toxins to catch prey and defend themselves against predators. However, little is …
[HTML][HTML] New Kunitz-Type HCRG Polypeptides from the Sea Anemone Heteractis crispa
I Gladkikh, M Monastyrnaya, E Zelepuga, O Sintsova… - Marine Drugs, 2015 - mdpi.com
Sea anemones are a rich source of Kunitz-type polypeptides that possess not only protease
inhibitor activity, but also Kv channels toxicity, analgesic, antihistamine, and anti …
inhibitor activity, but also Kv channels toxicity, analgesic, antihistamine, and anti …
Transcriptomic and proteomic analyses reveal the first occurrence of diverse toxin groups in Millepora alcicornis
VH Hérnández-Elizárraga, JE Vega-Tamayo… - Journal of …, 2023 - Elsevier
Millepora alcicornis is a reef-forming cnidarian widely distributed in the Mexican Caribbean.
Millepora species or “fire corals" inflict a painful stinging reaction in humans when touched …
Millepora species or “fire corals" inflict a painful stinging reaction in humans when touched …