[HTML][HTML] Silica nanoparticles: Biomedical applications and toxicity

Y Huang, P Li, R Zhao, L Zhao, J Liu, S Peng… - Biomedicine & …, 2022 - Elsevier
Silica nanoparticles (SiNPs) are composed of silicon dioxide, the most abundant compound
on Earth, and are used widely in many applications including the food industry, synthetic …

Prospects and hazards of silica nanoparticles: Biological impacts and implicated mechanisms

R Ding, Y Li, Y Yu, Z Sun, J Duan - Biotechnology Advances, 2023 - Elsevier
With the thrive of nanotechnology, silica nanoparticles (SiNPs) have been extensively
adopted in the agriculture, food, cosmetic, and even biomedical industries. Due to the mass …

Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway

F Wang, Q Liang, Y Ma, M Sun, T Li, L Lin, Z Sun… - Free Radical Biology …, 2022 - Elsevier
Growing literatures suggest that silica nanoparticles (SiNPs) exposure is correlated with
adverse cardiovascular effects. Cardiac hypertrophy is one of the most common risk factors …

Mitochondrial dysfunction in cardiovascular diseases: potential targets for treatment

J Yang, Q Guo, X Feng, Y Liu, Y Zhou - Frontiers in cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling

X Li, H Xu, X Zhao, Y Li, S Lv, W Zhou, J Wang… - Particle and fibre …, 2024 - Springer
Abstract Background Amorphous silica nanoparticles (SiNPs) have been gradually proven
to threaten cardiac health, but pathogenesis has not been fully elucidated. Ferroptosis is a …

Adverse effects of amorphous silica nanoparticles: focus on human cardiovascular health

C Guo, Y Liu, Y Li - Journal of Hazardous Materials, 2021 - Elsevier
Amorphous silica nanoparticle (SiNPs) has tremendous potential for a host of applications,
while its mass production, broad application and environmental release inevitably increase …

[HTML][HTML] Scalable generation of nanovesicles from human-induced pluripotent stem cells for cardiac repair

J Lozano, A Rai, JG Lees, H Fang, B Claridge… - International journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) from stem cells have shown significant therapeutic potential to
repair injured cardiac tissues and regulate pathological fibrosis. However, scalable …

State of the art of silica nanoparticles: an overview on biodistribution and preclinical toxicity studies

J Yu, N Dan, SM Eslami, X Lu - The AAPS Journal, 2024 - Springer
Over the past few years, nanoparticles have drawn particular attention in designing and
develo** drug delivery systems due to their distinctive advantages like improved …

Nanomaterials-induced toxicity on cardiac myocytes and tissues, and emerging toxicity assessment techniques

Y Cheng, Z Chen, S Yang, T Liu, L Yin, Y Pu… - Science of The Total …, 2021 - Elsevier
The extensive production and use of nanomaterials have resulted in the continuous release
of nano-sized particles into the environment, and the health risks caused by exposure to …

Too small to matter? Physicochemical transformation and toxicity of engineered nTiO2, nSiO2, nZnO, carbon nanotubes, and nAg

A Ahamed, L Liang, MY Lee, J Bobacka… - Journal of Hazardous …, 2021 - Elsevier
Engineered nanomaterials (ENMs) refer to a relatively novel class of materials that are
increasingly prevalent in various consumer products and industrial applications–most …