Early life adversity shapes neural circuit function during sensitive postnatal developmental periods

L Malave, MT van Dijk, C Anacker - Translational psychiatry, 2022 - nature.com
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

[HTML][HTML] COVID-19 in pregnancy: implications for fetal brain development

LL Shook, EL Sullivan, JO Lo, RH Perlis… - Trends in molecular …, 2022 - cell.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
during pregnancy on the develo** fetal brain is poorly understood. Other antenatal …

The serotonin system in autism spectrum disorder: From biomarker to animal models

CL Muller, AMJ Anacker, J Veenstra-VanderWeele - Neuroscience, 2016 - Elsevier
Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …

Placenta: the forgotten organ

E Maltepe, SJ Fisher - Annual review of cell and developmental …, 2015 - annualreviews.org
The placenta sits at the interface between the maternal and fetal vascular beds where it
mediates nutrient and waste exchange to enable in utero existence. Placental cells …

A transient placental source of serotonin for the fetal forebrain

A Bonnin, N Goeden, K Chen, ML Wilson, J King… - Nature, 2011 - nature.com
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is thought to regulate neurodevelopmental
processes through maternal–fetal interactions that have long-term mental health …

Transfer of maternal psychosocial stress to the fetus

F Rakers, S Rupprecht, M Dreiling, C Bergmeier… - Neuroscience & …, 2020 - Elsevier
Psychosocial maternal stress experienced during different vulnerable periods throughout
gestation is thought to increase the individual's risk to develop neuropsychiatric …

Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation

S Brummelte, E Mc Glanaghy, A Bonnin, TF Oberlander - Neuroscience, 2017 - Elsevier
Abstract The neurotransmitter serotonin (5-HT) plays a central role in brain development,
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …

Maternal inflammation disrupts fetal neurodevelopment via increased placental output of serotonin to the fetal brain

N Goeden, J Velasquez, KA Arnold… - Journal of …, 2016 - Soc Neuroscience
Maternal inflammation during pregnancy affects placental function and is associated with
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …

Development and critical period plasticity of the barrel cortex

RS Erzurumlu, P Gaspar - European Journal of Neuroscience, 2012 - Wiley Online Library
In primary sensory neocortical areas of mammals, the distribution of sensory receptors is
mapped with topographic precision and amplification in proportion to the peripheral receptor …

[HTML][HTML] Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism

J Nakatani, K Tamada, F Hatanaka, S Ise, H Ohta… - Cell, 2009 - cell.com
Substantial evidence suggests that chromosomal abnormalities contribute to the risk of
autism. The duplication of human chromosome 15q11-13 is known to be the most frequent …