Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
[HTML][HTML] COVID-19 in pregnancy: implications for fetal brain development
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
during pregnancy on the develo** fetal brain is poorly understood. Other antenatal …
during pregnancy on the develo** fetal brain is poorly understood. Other antenatal …
The serotonin system in autism spectrum disorder: From biomarker to animal models
Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …
Placenta: the forgotten organ
E Maltepe, SJ Fisher - Annual review of cell and developmental …, 2015 - annualreviews.org
The placenta sits at the interface between the maternal and fetal vascular beds where it
mediates nutrient and waste exchange to enable in utero existence. Placental cells …
mediates nutrient and waste exchange to enable in utero existence. Placental cells …
A transient placental source of serotonin for the fetal forebrain
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is thought to regulate neurodevelopmental
processes through maternal–fetal interactions that have long-term mental health …
processes through maternal–fetal interactions that have long-term mental health …
Transfer of maternal psychosocial stress to the fetus
F Rakers, S Rupprecht, M Dreiling, C Bergmeier… - Neuroscience & …, 2020 - Elsevier
Psychosocial maternal stress experienced during different vulnerable periods throughout
gestation is thought to increase the individual's risk to develop neuropsychiatric …
gestation is thought to increase the individual's risk to develop neuropsychiatric …
Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation
Abstract The neurotransmitter serotonin (5-HT) plays a central role in brain development,
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
Maternal inflammation disrupts fetal neurodevelopment via increased placental output of serotonin to the fetal brain
N Goeden, J Velasquez, KA Arnold… - Journal of …, 2016 - Soc Neuroscience
Maternal inflammation during pregnancy affects placental function and is associated with
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …
Development and critical period plasticity of the barrel cortex
In primary sensory neocortical areas of mammals, the distribution of sensory receptors is
mapped with topographic precision and amplification in proportion to the peripheral receptor …
mapped with topographic precision and amplification in proportion to the peripheral receptor …
[HTML][HTML] Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism
J Nakatani, K Tamada, F Hatanaka, S Ise, H Ohta… - Cell, 2009 - cell.com
Substantial evidence suggests that chromosomal abnormalities contribute to the risk of
autism. The duplication of human chromosome 15q11-13 is known to be the most frequent …
autism. The duplication of human chromosome 15q11-13 is known to be the most frequent …