Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …

Unmasking the subtleties of the immune system requires both a comprehensive knowledge
base and the ability to interrogate that system with intimate sensitivity. That task, to a …

While the antibody response to SARS-CoV-2 has been extensively studied in blood,
relatively little is known about the antibody response in saliva and its relationship to systemic …

INTRODUCTION Antibody function is often considered static and mostly determined by
isotype and subclass. The conserved N-linked glycan at position 297 in the Fc domain of …

Monoclonal antibodies (mAbs) are often selected from antigen-specific single B cells
derived from different hosts, which are notably short-lived in ex vivo culture conditions and …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Memory B cells are found in lymphoid and non-lymphoid tissues, suggesting that some may
be tissue-resident cells. Here we show that pulmonary influenza infection elicited lung …

Immunological memory is a composite of lasting antibody titers maintained by plasma cells
in conjunction with memory T and B cells. Memory B cells are a critical reservoir for plasma …

One of the most significant conceptual advances in immunology in recent history is the
recognition that signals from the innate immune system are required for induction of …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …