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Urinary tract infections: pathogenesis, host susceptibility and emerging therapeutics
MR Timm, SK Russell, SJ Hultgren - Nature Reviews Microbiology, 2024 - nature.com
Urinary tract infections (UTIs), which include any infection of the urethra, bladder or kidneys,
account for an estimated 400 million infections and billions of dollars in health-care …
account for an estimated 400 million infections and billions of dollars in health-care …
Enterococcus faecalis: an overlooked cell invader
Enterococcus faecalis and Enterococcus faecium are human pathobionts that exhibit a dual
lifestyle as commensal and pathogenic bacteria. The pathogenic lifestyle is associated with …
lifestyle as commensal and pathogenic bacteria. The pathogenic lifestyle is associated with …
Rapid and accurate testing for urinary tract infection: new clothes for the emperor
Urinary tract infection (UTI) is among the most common infections in clinical practice. In
some cases, if left untreated, it can lead to pyelonephritis and urosepsis. In other cases, UTI …
some cases, if left untreated, it can lead to pyelonephritis and urosepsis. In other cases, UTI …
A cynomolgus monkey E. coli urinary tract infection model confirms efficacy of new FimH vaccine candidates
L Chorro, T Ciolino, CL Torres, A Illenberger… - Infection and …, 2024 - journals.asm.org
The increase in urinary tract infections (UTI) caused by antibiotic-resistant Escherichia coli
requires the development of new therapeutic agents and prophylactic vaccines. To evaluate …
requires the development of new therapeutic agents and prophylactic vaccines. To evaluate …
Multispecies bacterial invasion of human host cells
Urinary tract infection (UTI), one of the most common bacterial infections worldwide, is a
typical example of an infection that is often polymicrobial in nature. While the overall …
typical example of an infection that is often polymicrobial in nature. While the overall …
Emerging models to study competitive interactions within bacterial communities
Within both abiotic and host environments, bacteria typically exist as diverse, multispecies
communities and have crucial roles in human health, agriculture, and industry. In these …
communities and have crucial roles in human health, agriculture, and industry. In these …
Bacterial adhesion strategies and countermeasures in urinary tract infection
C Flores, JL Rohn - Nature Microbiology, 2025 - nature.com
Urinary tract infections (UTIs) are compounded by antimicrobial resistance, which increases
the risk of UTI recurrence and antibiotic treatment failure. This also intensifies the burden of …
the risk of UTI recurrence and antibiotic treatment failure. This also intensifies the burden of …
Microbial communities, antibiotic resistance genes, and virulence factors in urinary infectious stone-associated urinary tract infections
Z Li, Z Zhang, P Yu, Y Ni - Urolithiasis, 2024 - Springer
Urinary infectious stones are challenging due to bacterial involvement, necessitating a
comprehensive understanding of these conditions. Antibiotic-resistant urease-producing …
comprehensive understanding of these conditions. Antibiotic-resistant urease-producing …
Human-relevant urothelial model provides insight into infection strategies and host response
L Lloyd - Nature Reviews Urology, 2024 - nature.com
Use of a 3D urine-tolerant human urothelial model (3D-UHU), which recapitulates the crucial
features of human urothelium, has enabled characterization and improved understanding of …
features of human urothelium, has enabled characterization and improved understanding of …
Elucidating Enterococcal Mechanisms Underlying Recurrent Urinary Tract Infections
B Hochstedler-Kramer - 2024 - ecommons.luc.edu
Urinary tract infection (UTI) is one of the most common bacterial infections globally and can
lead to life-threatening complications. UTI disproportionately affects females, with the …
lead to life-threatening complications. UTI disproportionately affects females, with the …