Enzyme replacement therapy (ERT) has been used to treat a few of the many existing
diseases which are originated from the lack of, or low enzymatic activity. Exogenous …

Protein-polymer conjugates are complex molecules with major societal implications. Many
advances in the fields of medicine, biotechnology and nanotechnology have been …

Protein nanoparticle scaffolds are increasingly used in next-generation vaccine designs,
and several have established records of clinical safety and efficacy. Yet the rules for how …

Despite the success of vaccines in preventing many infectious diseases, effective vaccines
against pathogens with ongoing challenges—such as HIV, malaria, and tuberculosis …

Multiple advanced formulations and drug delivery systems (DDSs) have been developed to
deliver protein-based biotherapeutics via the subcutaneous (SC) route. These …

Virus-like particles (VLPs) constitute large, polyvalent platforms onto which a wide variety of
functional units can be grafted. Their use in biological settings often depends on their …

Proteins, having miscellaneous properties perfected by nature over millions of years, are
attractive for many biomedical and industrial applications. The exploitation of proteins offers …

Protein-polymer conjugates (PPCs) improve therapeutic efficacy of proteins and have been
widely used for the treatment of various diseases such as cancer, diabetes, and hepatitis …

Virus-like particles (VLPs) are emerging as nanoscaffolds in a variety of biomedical
applications including delivery of vaccine antigens and cargo such as mRNA to mucosal …

This study explores the synthesis and application of artificial zymogens using protein–
polymer hybrids to mimic the controlled enzyme activation observed in natural zymogens …