Morpholines. Synthesis and biological activity
VA Pal'Chikov - Russian Journal of Organic Chemistry, 2013 - Springer
The review analyzes methods of synthesis of 1, 4-oxazines (morpholines) starting from
vicinal amino alcohols and their derivatives, oxiranes, and aziridines. Examples of using …
vicinal amino alcohols and their derivatives, oxiranes, and aziridines. Examples of using …
[PDF][PDF] A review on pharmacological profile of morpholine derivatives
Morpholine, an aromatic organic heterocycle scaffold possesses one nitrogen & an oxygen
atoms of six-membered ring. It is a multipurpose lead compound developed by chemical …
atoms of six-membered ring. It is a multipurpose lead compound developed by chemical …
Potential bacterial biofilm, MRSA, and DHFR inhibitors based on new morpholine-linked chromene-thiazole hybrids: One-pot synthesis and in silico study
We report herein the utility of the morpholine-linked benzaldehyde as a key building block in
the preparation of two series of new chromene-thiazoles with potential bioactivities. In this …
the preparation of two series of new chromene-thiazoles with potential bioactivities. In this …
Synthesis and antioxidant activity evaluation of some novel aminocarbonitrile derivatives incorporating carbohydrate moieties
S Khajeh Dangolani, F Panahi, Z Tavaf… - ACS …, 2018 - ACS Publications
In this study, a multicomponent reaction involving carbohydrates, β-dicarbonyl compounds,
and malononitrile was disclosed to synthesize a new class of polyhydroxy compounds …
and malononitrile was disclosed to synthesize a new class of polyhydroxy compounds …
Novel fluorene/fluorenone DNA and RNA binders as efficient non-toxic ds-RNA selective fluorescent probes
A series of structurally similar 1-substitued heteroaryl fluorene derivatives were prepared in
a simple single step reaction, oxidized to fluorenones and then both, fluorenes and …
a simple single step reaction, oxidized to fluorenones and then both, fluorenes and …
Unexpected dihydropyridinium derivatives using a multicomponent reaction containing unprotected amino acids
SK Dangolani, E Niknam, O Shahraki… - Journal of Molecular …, 2021 - Elsevier
In this study, a multicomponent reaction (MCR) of amino acids, aldehydes, β-dicarbonyl
compounds, and malononitrile is presented to obtain a novel class of dihydropyridinium …
compounds, and malononitrile is presented to obtain a novel class of dihydropyridinium …
Synthesis of biologically active heterocycles via a domino sequence involving an SN2/Thorpe–Ziegler Reaction Step
NA Larionova, AM Shestopalov, LA Rodinovskaya… - …, 2022 - thieme-connect.com
This review highlights methods for the synthesis of five-and six-membered heterocycles and
their annulated analogues. These methods are based on anionic domino reactions that …
their annulated analogues. These methods are based on anionic domino reactions that …
Facile one-pot synthesis of novel ortho-aminocarbonitriles and dicyanoanilines fused to heterocycles via pseudo four-component reactions
Methylpiperidin-4-one and its sulfur and oxygen analogues undergo individual facile
pseudo four-component reactions with two folds of malononitrile and various aldehydes by …
pseudo four-component reactions with two folds of malononitrile and various aldehydes by …
CoFe2O4@SiO2‐PA‐CC‐guanidine nanoparticles: A novel, efficient, and recyclable catalyst for the synthesis of 3,5‐disubstituted‐2,6‐dicyanoaniline derivatives
H Rostami, L Shiri - Applied Organometallic Chemistry, 2020 - Wiley Online Library
A new and efficient procedure for the synthesis of 3, 5‐disubstituted‐2, 6‐dicyanoaniline
derivatives by CoFe2O4@ SiO2‐PA‐CC‐guanidine magnetic nanoparticles (MNPs) was …
derivatives by CoFe2O4@ SiO2‐PA‐CC‐guanidine magnetic nanoparticles (MNPs) was …
Synthesis of Substituted 2, 6-Dicyanoanilines and Related Compounds. A Review
HB Borate, AS Kudale, SG Agalave - Organic Preparations and …, 2012 - Taylor & Francis
Substituted 2, 6-dicyanoanilines constitute an important group of useful compounds with
acceptor-donor-acceptor (ADA) systems having varied applications. Many of the compounds …
acceptor-donor-acceptor (ADA) systems having varied applications. Many of the compounds …