Parental education and inequalities in child mortality: a global systematic review and meta-analysis

M Balaj, HW York, K Sripada, E Besnier, HD Vonen… - The Lancet, 2021 - thelancet.com
Background The educational attainment of parents, particularly mothers, has been
associated with lower levels of child mortality, yet there is no consensus on the magnitude of …

Runs of homozygosity: windows into population history and trait architecture

FC Ceballos, PK Joshi, DW Clark, M Ramsay… - Nature Reviews …, 2018 - nature.com
Long runs of homozygosity (ROH) arise when identical haplotypes are inherited from each
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

A Okbay, Y Wu, N Wang, H Jayashankar, M Bennett… - Nature …, 2022 - nature.com
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke… - Nature …, 2019 - nature.com
Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via
poorly understood mechanisms. We performed a trans-ancestry genome-wide association …

Innovation in the collective brain

M Muthukrishna, J Henrich - … Transactions of the Royal …, 2016 - royalsocietypublishing.org
Innovation is often assumed to be the work of a talented few, whose products are passed on
to the masses. Here, we argue that innovations are instead an emergent property of our …

The evolution of general intelligence

JM Burkart, MN Schubiger… - Behavioral and Brain …, 2017 - cambridge.org
The presence of general intelligence poses a major evolutionary puzzle, which has led to
increased interest in its presence in nonhuman animals. The aim of this review is to critically …

Cross-species comparisons of host genetic associations with the microbiome

JK Goodrich, ER Davenport, JL Waters, AG Clark… - Science, 2016 - science.org
Recent studies in human populations and mouse models reveal notable congruences in gut
microbial taxa whose abundances are partly regulated by host genotype. Host genes …

[HTML][HTML] The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

M Laakso, J Kuusisto, A Stančáková, T Kuulasmaa… - Journal of lipid …, 2017 - Elsevier
The Metabolic Syndrome in Men (METSIM) study is a population-based study including
10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate …

Inbreeding depression across the lifespan in a wild mammal population

J Huisman, LEB Kruuk, PA Ellis, T Clutton-Brock… - Proceedings of the …, 2016 - pnas.org
Inbreeding depression is of major concern for the conservation of threatened species, and
inbreeding avoidance is thought to be a key driver in the evolution of mating systems …

Cohort profile: the Western Australian pregnancy cohort (Raine) study–generation 2

L Straker, J Mountain, A Jacques… - International journal …, 2017 - academic.oup.com
The Western Australian Pregnancy Cohort (Raine) Study (www. rainestudy. org. au) was
established 1989-1991 with the then stated purpose: to develop a large cohort of Western …