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Parental education and inequalities in child mortality: a global systematic review and meta-analysis
Background The educational attainment of parents, particularly mothers, has been
associated with lower levels of child mortality, yet there is no consensus on the magnitude of …
associated with lower levels of child mortality, yet there is no consensus on the magnitude of …
Runs of homozygosity: windows into population history and trait architecture
Long runs of homozygosity (ROH) arise when identical haplotypes are inherited from each
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via
poorly understood mechanisms. We performed a trans-ancestry genome-wide association …
poorly understood mechanisms. We performed a trans-ancestry genome-wide association …
Innovation in the collective brain
Innovation is often assumed to be the work of a talented few, whose products are passed on
to the masses. Here, we argue that innovations are instead an emergent property of our …
to the masses. Here, we argue that innovations are instead an emergent property of our …
The evolution of general intelligence
The presence of general intelligence poses a major evolutionary puzzle, which has led to
increased interest in its presence in nonhuman animals. The aim of this review is to critically …
increased interest in its presence in nonhuman animals. The aim of this review is to critically …
Cross-species comparisons of host genetic associations with the microbiome
Recent studies in human populations and mouse models reveal notable congruences in gut
microbial taxa whose abundances are partly regulated by host genotype. Host genes …
microbial taxa whose abundances are partly regulated by host genotype. Host genes …
[HTML][HTML] The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases
The Metabolic Syndrome in Men (METSIM) study is a population-based study including
10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate …
10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate …
Inbreeding depression across the lifespan in a wild mammal population
Inbreeding depression is of major concern for the conservation of threatened species, and
inbreeding avoidance is thought to be a key driver in the evolution of mating systems …
inbreeding avoidance is thought to be a key driver in the evolution of mating systems …
Cohort profile: the Western Australian pregnancy cohort (Raine) study–generation 2
The Western Australian Pregnancy Cohort (Raine) Study (www. rainestudy. org. au) was
established 1989-1991 with the then stated purpose: to develop a large cohort of Western …
established 1989-1991 with the then stated purpose: to develop a large cohort of Western …