This article reviews the past and current statuses of time-domain near-infrared spectroscopy
(TD-NIRS) and imaging. Although time-domain technology is not yet widely employed due to …

This review presents recent developments and a wide overview of broadband time domain
diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration …

Significance: The ability of diffuse correlation spectroscopy (DCS) to measure cerebral blood
flow (CBF) in humans is hindered by the low signal-to-noise ratio (SNR) of the method. This …

We report on the design, development, and performance assessment of a portable time-
resolved system measuring absorption and scattering spectra of highly diffusive media over …

Clinical studies have demonstrated that epidermal pigmentation level can affect cerebral
oximetry measurements. To evaluate the robustness of these devices, we have developed a …

Near-infrared spectroscopy (NIRS) is an established technique for measuring tissue oxygen
saturation (StO_2), which is of high clinical value. For tissues that have layered structures, it …

Diffuse correlation spectroscopy (DCS) is a non-invasive optical technology for the
assessment of an index of cerebral blood flow (CBFi). Analytical methods that model the …

We investigate a scheme for noninvasive continuous monitoring of absolute cerebral blood
flow (CBF) in adult human patients based on a combination of time-resolved dynamic …

There is a growing interest in the possibility of using functional neuroimaging techniques to
aid in detecting covert awareness in patients who are thought to be suffering from a disorder …

Significance: The use of diffuse correlation spectroscopy (DCS) has shown efficacy in
research studies as a technique capable of noninvasively monitoring blood flow in tissue …